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精液分析:男性生育状况恰当评估的工作流程。

Semen analysis: a workflow for an appropriate assessment of the male fertility status.

作者信息

Crafa Andrea, Cannarella Rossella, LA Vignera Sandro, Barbagallo Federica, Condorelli Rosita A, Calogero Aldo E

机构信息

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy -

出版信息

Minerva Endocrinol (Torino). 2022 Mar;47(1):77-88. doi: 10.23736/S2724-6507.21.03650-2. Epub 2021 Nov 26.

DOI:10.23736/S2724-6507.21.03650-2
PMID:34825558
Abstract

Infertility is a worldwide problem that affects 9-15% of couples in reproductive age. In about half of the cases, it recognizes, alone or in combination, a male cause. In addition to a reproductive problem, male infertility can result from a systemic disease. Consequently, semen analysis, a fundamental test in the diagnosis of male infertility, represents a useful indicator not only of a man's reproductive capacity but also of his health and lifestyle. Given the key role of semen analysis, only accredited laboratories should perform it and experienced clinicians should be called into play in its interpretation. In this article, we have extensively examined how the macroscopic and microscopic parameters of semen analysis, alone or associated with each other, allow clinicians to orient towards specific diagnoses that can be confirmed by further ad-hoc tests. On this basis, we also proposed a diagnostic flowchart focused on the results of the semen analysis.

摘要

不孕症是一个全球性问题,影响着9%至15%的育龄夫妇。在大约一半的病例中,可单独或联合发现男性因素。除了生殖问题外,男性不育还可能由全身性疾病引起。因此,精液分析作为男性不育诊断的一项基本检查,不仅是男性生殖能力的有用指标,也是其健康和生活方式的指标。鉴于精液分析的关键作用,只有经过认可的实验室才能进行此项检查,且应由经验丰富的临床医生对其结果进行解读。在本文中,我们广泛探讨了精液分析的宏观和微观参数如何单独或相互关联,使临床医生能够朝着可通过进一步的专门检查得到证实的特定诊断方向进行判断。在此基础上,我们还提出了一个以精液分析结果为重点的诊断流程图。

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Semen analysis: a workflow for an appropriate assessment of the male fertility status.精液分析:男性生育状况恰当评估的工作流程。
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Novel concepts in the aetiology of male reproductive impairment.男性生殖障碍病因学的新概念。
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[Semen analysis in involuntary childlessness. What information does it provide?].[非自愿性不育中的精液分析。它能提供哪些信息?]
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Nutrients. 2024 Nov 29;16(23):4129. doi: 10.3390/nu16234129.
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Global, regional and national burden of male infertility in 204 countries and territories between 1990 and 2019: an analysis of global burden of disease study.全球、区域和国家 1990 年至 2019 年男性不育症负担:疾病负担研究全球分析。
BMC Public Health. 2023 Nov 8;23(1):2195. doi: 10.1186/s12889-023-16793-3.
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The Impact of a Very Short Abstinence Period on Conventional Sperm Parameters and Sperm DNA Fragmentation: A Systematic Review and Meta-Analysis.
极短禁欲期对常规精子参数和精子DNA碎片化的影响:一项系统评价和荟萃分析。
J Clin Med. 2022 Dec 8;11(24):7303. doi: 10.3390/jcm11247303.
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Physical Examination for Endocrine Diseases: Does It Still Play a Role?内分泌疾病的体格检查:它仍发挥作用吗?
J Clin Med. 2022 May 5;11(9):2598. doi: 10.3390/jcm11092598.