Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Beijing University of Traditional Chinese Medicine, Beijing, China.
Integr Cancer Ther. 2021 Jan-Dec;20:15347354211061720. doi: 10.1177/15347354211061720.
Esophageal cancer (EC) is the sixth leading cause of cancer-related deaths worldwide. Western medicine has played a leading role in its treatment, but its prognosis remains unsatisfactory. Therefore, the development of effective therapies is important. Traditional Chinese medicine (TCM) has been practiced for thousands of years, and involves taking measures before diseases occur, deteriorate, and recur. Interestingly, there is growing evidence that TCM can improve the therapeutic effects in reversing precancerous lesions, inhibiting the recurrence and metastasis of EC. In this article, we review traditional Chinese herbs and formulas that have preventive and therapeutic effects on EC, summarize the application and research status of TCM in patients with EC, and discuss its shortcomings and prospects in the context of translational, evidence-based, and precision medicine.
食管癌(EC)是全球第六大癌症相关死亡原因。西医在其治疗中发挥了主导作用,但预后仍不理想。因此,开发有效的治疗方法很重要。中医药已有数千年的历史,涉及在疾病发生、恶化和复发之前采取措施。有趣的是,越来越多的证据表明,中医药可以提高逆转癌前病变、抑制食管癌复发和转移的治疗效果。本文综述了具有预防和治疗食管癌作用的中药和方剂,总结了中医药在食管癌患者中的应用和研究现状,并结合转化医学、循证医学和精准医学探讨了其不足和前景。