Burgio G R, Martini A
Department of Pediatrics, University of Pavia, Italy.
Scand J Rheumatol Suppl. 1987;66:5-11. doi: 10.3109/03009748709102516.
The high degree of polymorphism of the genes controlling the immune system makes immune reactivity of any being very individualized. Self non self recognition, rejection of non-self is the most clear and common expression of this individuality. Moreover antigen experience, chance and even psychological conditions may further affect the immune response characteristics so contributing to enhance the individuality of the "way of reacting" and, therefore, of susceptibility to immune-mediated diseases. In this perspective man can consider himself as a true biological ego.
控制免疫系统的基因具有高度多态性，这使得任何生物的免疫反应都极具个体性。自我与非自我的识别、对非自我的排斥是这种个体性最明显和常见的表现。此外，抗原体验、机遇甚至心理状况都可能进一步影响免疫反应特征，从而有助于增强“反应方式”的个体性，进而增强对免疫介导疾病的易感性。从这个角度来看，人类可以将自己视为一个真正的生物自我。
