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法医学中的 DNA 转移:应对挑战的最新进展。

DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges.

机构信息

Office of the Chief Forensic Scientist, Victoria Police Forensic Services Department, Macleod, VIC 3085, Australia.

School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.

出版信息

Genes (Basel). 2021 Nov 7;12(11):1766. doi: 10.3390/genes12111766.

Abstract

Understanding the factors that may impact the transfer, persistence, prevalence and recovery of DNA (DNA-TPPR), and the availability of data to assign probabilities to DNA quantities and profile types being obtained given particular scenarios and circumstances, is paramount when performing, and giving guidance on, evaluations of DNA findings given activity level propositions (activity level evaluations). In late 2018 and early 2019, three major reviews were published on aspects of DNA-TPPR, with each advocating the need for further research and other actions to support the conduct of DNA-related activity level evaluations. Here, we look at how challenges are being met, primarily by providing a synopsis of DNA-TPPR-related articles published since the conduct of these reviews and briefly exploring some of the actions taken by industry stakeholders towards addressing identified gaps. Much has been carried out in recent years, and efforts continue, to meet the challenges to continually improve the capacity of forensic experts to provide the guidance sought by the judiciary with respect to the transfer of DNA.

摘要

了解可能影响 DNA(DNA-TPPR)转移、持久性、流行率和恢复的因素,以及在特定场景和情况下获得特定 DNA 数量和谱型概率的可用数据,对于进行和指导 DNA 结果的评估至关重要给定活动水平命题(活动水平评估)。2018 年末和 2019 年初,发表了三篇关于 DNA-TPPR 各个方面的主要综述,每篇综述都主张需要进一步研究和采取其他行动来支持进行与 DNA 相关的活动水平评估。在这里,我们着眼于如何应对挑战,主要是通过总结自这些综述以来发表的与 DNA-TPPR 相关的文章,并简要探讨行业利益相关者为解决已确定的差距而采取的一些行动。近年来,已经开展了许多工作,并将继续努力,以应对挑战,不断提高法医专家的能力,为司法机构提供关于 DNA 转移的咨询意见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8238/8618004/efd3218b0726/genes-12-01766-g001.jpg

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