Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Osypovskoho Str. 2a, 04123 Kyiv, Ukraine.
Int J Mol Sci. 2021 Nov 11;22(22):12202. doi: 10.3390/ijms222212202.
Ag-based quantum dots (QDs) are semiconductor nanomaterials with exclusive electrooptical properties ideally adaptable for various biotechnological, chemical, and medical applications. Silver-based semiconductor nanocrystals have developed rapidly over the past decades. They have become a promising luminescent functional material for in vivo and in vitro fluorescent studies due to their ability to emit at the near-infrared (NIR) wavelength. In this review, we discuss the basic features of Ag-based QDs, the current status of classic (chemical) and novel methods ("green" synthesis) used to produce these QDs. Additionally, the advantages of using such organisms as bacteria, actinomycetes, fungi, algae, and plants for silver-based QDs biosynthesis have been discussed. The application of silver-based QDs as fluorophores for bioimaging application due to their fluorescence intensity, high quantum yield, fluorescent stability, and resistance to photobleaching has also been reviewed.
基于银的量子点（QDs）是具有独特光电特性的半导体纳米材料，非常适合各种生物技术、化学和医学应用。在过去的几十年中，基于银的半导体纳米晶体发展迅速。由于它们能够在近红外（NIR）波长处发射，因此成为用于体内和体外荧光研究的有前途的发光功能材料。在这篇综述中，我们讨论了基于银的 QDs 的基本特征，以及目前用于生产这些 QDs 的经典（化学）和新型方法（“绿色”合成）的现状。此外，还讨论了利用细菌、放线菌、真菌、藻类和植物等生物体来合成银基 QDs 的优势。还综述了基于银的 QDs 作为荧光团在生物成像应用中的应用，因为它们具有荧光强度高、量子产率高、荧光稳定性好和抗光漂白性。
