Offi Chiara, Misso Claudia, Antonelli Giovanni, Esposito Maria Grazia, Brancaccio Umberto, Spiezia Stefano
Department of Endocrine and Ultrasound-Guided Surgery, Ospedale del Mare, 80147 Naples, Italy.
J Clin Med. 2021 Nov 14;10(22):5295. doi: 10.3390/jcm10225295.
(1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high rate of complications. Therefore, laser ablation of recurrent lymph nodes has been recognized as an alternative treatment with minimal invasiveness, a low complication rate and a curative effect. (2) Methods: We analyzed 10 patients who underwent a total thyroidectomy and metabolic radiotherapy and who developed a lymph node recurrence in the laterocervical compartment in the following 12-18 months. (3) Results: Patients developed lymph node recurrence at IV and Vb levels in 70% and 30% of cases, respectively. All patients were treated with a single laser ablative session. Hydrodissection was performed in all patients. The energy delivered was 1120 ± 159.3 Joules and 3-4 Watts in 362 ± 45.7 s. No complications were reported. All patients underwent a 6-month follow-up. A volumetric reduction of 40.12 ± 2.2%, 49.1 ± 2.13% and 59.8 ± 3.05%, respectively at 1-, 3- and 6-months of follow-up was reported. (4) Conclusions: At 6 months, a fine needle aspiration was performed, which was negative for malignant cells and negative for a dosage of Thyroglobulin in eluate. The laser ablation is an effective alternative to surgical treatment.
(1)背景:甲状腺乳头状癌的发病率正在上升。乳头状肿瘤会转移至颈部中央和外侧淋巴结。复发率低于30%。淋巴结复发的治疗金标准是手术,但手术并发症发生率高。因此,复发性淋巴结的激光消融已被公认为是一种微创、低并发症率且有治愈效果的替代治疗方法。(2)方法:我们分析了10例接受全甲状腺切除术和代谢放疗且在随后12至18个月出现颈外侧区淋巴结复发的患者。(3)结果:患者分别在IV级和Vb级出现淋巴结复发的病例占70%和30%。所有患者均接受单次激光消融治疗。所有患者均进行了水分离术。输送的能量为1120±159.3焦耳,在362±45.7秒内为3至4瓦。未报告并发症。所有患者均接受了6个月的随访。随访1个月、3个月和6个月时,报告的体积分别减少了40.12±2.2%、49.1±2.13%和59.8±3.05%。(4)结论:在6个月时进行了细针穿刺抽吸,结果显示洗脱液中恶性细胞为阴性,甲状腺球蛋白剂量为阴性。激光消融是手术治疗的一种有效替代方法。