Arshad Mahnaz, Khayat Zadeh Sina, Atai Mohammad, Shirani Gholamreza, Romanos Georgios E, Bassir Seyed Hossein
Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran 14155-6447, Iran.
Department of Prosthodontics, School of Dentistry, International Campus, Tehran University of Medical Sciences, Tehran 14399-55991, Iran.
Materials (Basel). 2021 Nov 12;14(22):6832. doi: 10.3390/ma14226832.
The aim of this study was to assess the effect of application of a recently developed bio-adhesive (Impladhesive) to abutment screw threads on the removal torque value and rotational misfit at the implant-abutment junction. This in vitro study evaluated 20 implant fixtures and 20 straight abutments. Specimens were randomly divided into two groups ( = 10) with/without adhesive application. In the adhesive group, the abutment was dipped in Impladhesive before torquing. In the control group, the abutment was torqued conventionally without adhesive application. The removal torque value was recorded after completion of the cyclic loading of 500,000 cycles with 2 Hz frequency and 75 N load. Rotational misfit was recorded using a video measuring machine. After applying the torque, the change in the bisector angle on the abutment hex was recorded for each implant. The biocompatibility of Impladhesive was evaluated using a MTT cell vitality assay. Normal distribution of data was assessed using the Kolmogorov-Smirnov test. Data were analyzed using a -test and Pearson's correlation coefficient The application of Impladhesive at the implant-abutment interface resulted in significantly greater mean removal torque value compared to the control group ( = 0.008). In addition, the mean rotational misfit at the implant-abutment interface was significantly lower in the use of Impladhesive compared to the control group ( = 0.001). In addition, the cell vitality was found to be greater than 80% at all evaluated time points. It can be concluded that the application of Impladhesive on the abutment screw significantly decreased rotational misfit and increased the removal torque value. Future studies are needed to evaluate the efficacy of this bio-adhesive an in vivo setting.
本研究的目的是评估一种最新研发的生物粘合剂（Impladhesive）应用于基台螺纹对种植体-基台连接处的拆卸扭矩值和旋转不匹配的影响。这项体外研究评估了20个种植体固定装置和20个直基台。样本被随机分为两组（每组n = 10），一组应用粘合剂，另一组不应用粘合剂。在粘合剂组中，在施加扭矩前将基台浸入Impladhesive中。在对照组中，基台按常规方式施加扭矩，不使用粘合剂。在以2 Hz频率和75 N载荷完成500,000次循环加载后，记录拆卸扭矩值。使用视频测量仪记录旋转不匹配情况。施加扭矩后，记录每个种植体基台六角上平分线角度的变化。使用MTT细胞活力测定法评估Impladhesive的生物相容性。使用Kolmogorov-Smirnov检验评估数据的正态分布。使用t检验和Pearson相关系数分析数据。与对照组相比，在种植体-基台界面应用Impladhesive导致平均拆卸扭矩值显著更高（P = 0.008）。此外，与对照组相比，使用Impladhesive时种植体-基台界面的平均旋转不匹配显著更低（P = 0.001）。此外，在所有评估时间点，细胞活力均大于80%。可以得出结论，在基台螺钉上应用Impladhesive可显著降低旋转不匹配并增加拆卸扭矩值。未来需要进行研究以评估这种生物粘合剂在体内环境中的疗效。
