用于理解脑部疾病的多组学技术
Multi-Omics for the Understanding of Brain Diseases.
作者信息
Villa Chiara, Yoon Jong Hyuk
机构信息
School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Neurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu 41062, Korea.
出版信息
Life (Basel). 2021 Nov 7;11(11):1202. doi: 10.3390/life11111202.
Abstract
Brain diseases, including both neurodegenerative diseases and mental disorders, represent the third largest healthcare problem in developed countries, after cardiovascular disorders and cancer [...].
摘要
脑部疾病，包括神经退行性疾病和精神障碍，是发达国家继心血管疾病和癌症之后的第三大医疗保健问题。
相似文献
1
Multi-Omics for the Understanding of Brain Diseases.
Life (Basel). 2021 Nov 7;11(11):1202. doi: 10.3390/life11111202.
2
Relevance of Multi-Omics Studies in Cardiovascular Diseases.
Front Cardiovasc Med. 2019 Jul 17;6:91. doi: 10.3389/fcvm.2019.00091. eCollection 2019.
3
Gut microbiome-mediated epigenetic regulation of brain disorder and application of machine learning for multi-omics data analysis.
Genome. 2021 Apr;64(4):355-371. doi: 10.1139/gen-2020-0136. Epub 2020 Oct 8.
4
Integration of multi-omics data for integrative gene regulatory network inference.
Int J Data Min Bioinform. 2017;18(3):223-239. doi: 10.1504/IJDMB.2017.10008266. Epub 2017 Oct 3.
5
MONTI: A Multi-Omics Non-negative Tensor Decomposition Framework for Gene-Level Integrative Analysis.
Front Genet. 2021 Sep 10;12:682841. doi: 10.3389/fgene.2021.682841. eCollection 2021.
6
A survey on single and multi omics data mining methods in cancer data classification.
J Biomed Inform. 2020 Jul;107:103466. doi: 10.1016/j.jbi.2020.103466. Epub 2020 Jun 7.
7
A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping.
Brief Bioinform. 2020 Dec 1;21(6):1920-1936. doi: 10.1093/bib/bbz121.
8
Min-redundancy and max-relevance multi-view feature selection for predicting ovarian cancer survival using multi-omics data.
BMC Med Genomics. 2018 Sep 14;11(Suppl 3):71. doi: 10.1186/s12920-018-0388-0.
9
PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data.
BMC Bioinformatics. 2020 Apr 16;21(1):146. doi: 10.1186/s12859-020-3465-2.
10
Integrated multi-omics analysis of ovarian cancer using variational autoencoders.
Sci Rep. 2021 Mar 18;11(1):6265. doi: 10.1038/s41598-021-85285-4.
引用本文的文献
1
Integrative approach of omics and imaging data to discover new insights for understanding brain diseases.
Brain Commun. 2024 Aug 8;6(4):fcae265. doi: 10.1093/braincomms/fcae265. eCollection 2024.
2
Single-cell and spatial omics: exploring hypothalamic heterogeneity.
Neural Regen Res. 2025 Jun 1;20(6):1525-1540. doi: 10.4103/NRR.NRR-D-24-00231. Epub 2024 Jul 10.
3
Integrative Analysis Unveils the Correlation of Aminoacyl-tRNA Biosynthesis Metabolites with the Methylation of the Gene in Huntington's Disease Brain Tissue.
Genes (Basel). 2023 Sep 2;14(9):1752. doi: 10.3390/genes14091752.
4
Integrative multi-omics and systems bioinformatics in translational neuroscience: A data mining perspective.
J Pharm Anal. 2023 Aug;13(8):836-850. doi: 10.1016/j.jpha.2023.06.011. Epub 2023 Jun 30.
5
Opportunities and challenges of 5G network technology toward precision medicine.
Clin Transl Sci. 2023 Nov;16(11):2078-2094. doi: 10.1111/cts.13640. Epub 2023 Sep 25.
6
Machine Learning Model Based on Lipidomic Profile Information to Predict Sudden Infant Death Syndrome.
Healthcare (Basel). 2022 Jul 14;10(7):1303. doi: 10.3390/healthcare10071303.
7
Segmentation of Drug-Treated Cell Image and Mitochondrial-Oxidative Stress Using Deep Convolutional Neural Network.
Oxid Med Cell Longev. 2022 May 26;2022:5641727. doi: 10.1155/2022/5641727. eCollection 2022.
本文引用的文献
1
Microfluidic Platforms to Unravel Mysteries of Alzheimer's Disease: How Far Have We Come?
Life (Basel). 2021 Sep 28;11(10):1022. doi: 10.3390/life11101022.
2
Proteomic Analysis Unveils Expressional Changes in Cytoskeleton- and Synaptic Plasticity-Associated Proteins in Rat Brain Six Months after Withdrawal from Morphine.
Life (Basel). 2021 Jul 13;11(7):683. doi: 10.3390/life11070683.
3
Description of a CSF-Enriched miRNA Panel for the Study of Neurological Diseases.
Life (Basel). 2021 Jun 22;11(7):594. doi: 10.3390/life11070594.
4
Proteins Alleviate Hydrogen Peroxide Stress in SH-SY5Y Cells.
Life (Basel). 2021 Jun 20;11(6):585. doi: 10.3390/life11060585.
5
Spatiotemporal 22q11.21 Protein Network Implicates DGCR8-Dependent MicroRNA Biogenesis as a Risk for Late-Fetal Cortical Development in Psychiatric Diseases.
Life (Basel). 2021 May 31;11(6):514. doi: 10.3390/life11060514.
6
NADomics: Measuring NAD and Related Metabolites Using Liquid Chromatography Mass Spectrometry.
Life (Basel). 2021 May 31;11(6):512. doi: 10.3390/life11060512.
7
Omics Data and Their Integrative Analysis to Support Stratified Medicine in Neurodegenerative Diseases.
Int J Mol Sci. 2021 May 1;22(9):4820. doi: 10.3390/ijms22094820.
8
Integrating molecular, histopathological, neuroimaging and clinical neuroscience data with NeuroPM-box.
Commun Biol. 2021 May 21;4(1):614. doi: 10.1038/s42003-021-02133-x.
9
Human Brain Lipidomics: Utilities of Chloride Adducts in Flow Injection Analysis.
Life (Basel). 2021 Apr 28;11(5):403. doi: 10.3390/life11050403.
10
Integrative Analysis Identified Key Schizophrenia Risk Factors from an Abnormal Behavior Mouse Gene Set.
Life (Basel). 2021 Feb 23;11(2):172. doi: 10.3390/life11020172.
Zotero 插件