Department of Obstetrics and Gynecology, "Alessandrescu-Rusescu" National Institute of Mother and Child Care, 050474 Bucharest, Romania.
Department of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Medicina (Kaunas). 2021 Nov 16;57(11):1253. doi: 10.3390/medicina57111253.
Tracheal atresia is an extremely rare condition whereby a partial or total obstruction of the trachea is seen. It is almost always lethal, with just a handful of cases that ended with a good outcome. In this study we report on a 15-week male fetus, diagnosed with hyperechogenic lungs, midline heart position and inverted diaphragm. Sonographic findings suggest congenital High Airway Obstruction Syndrome (CHAOS) An ultrasound scan and fetal MRI were not able to point out the exact obstruction level. In spite of extensive counselling, the parents opted to carry on with the pregnancy. Fetal demise was noted on a scan at 19 weeks gestation. After the elective termination of pregnancy, a post-mortem examination showed partial tracheal atresia with no other anomalies. Despite technological progress in CHAOS syndrome, a precise diagnosis and accurate prognosis remain elusive.
气管闭锁是一种极其罕见的情况，可见部分或完全的气管阻塞。它几乎总是致命的，只有少数病例有良好的结局。在本研究中，我们报告了一例 15 周的男性胎儿，超声检查提示肺部回声增强、心脏位于中线位置和膈肌倒置。超声检查结果提示先天性高位气道阻塞综合征（CHAOS）。超声和胎儿 MRI 均未能明确梗阻部位。尽管进行了广泛的咨询，父母仍选择继续妊娠。在妊娠 19 周的扫描中发现胎儿死亡。选择性终止妊娠后，尸检显示部分气管闭锁，无其他异常。尽管在 CHAOS 综合征方面取得了技术进步，但仍难以做出精确的诊断和准确的预后。
