Masselli Gabriele, Di Bella Chiara, Hadjidekov George, Carnelli Carlos, Morini Francesco, Ceccanti Silvia, Midulla Fabio, Cozzi Denis A
Department of Radiological Sciences, Oncology and Pathology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Department of Physics, Biophysics and Radiology, Medical Faculty, Sofia University St. Kliment Ohridski, 1407 Sofia, Bulgaria.
Diagnostics (Basel). 2025 Apr 27;15(9):1112. doi: 10.3390/diagnostics15091112.
Pediatric congenital lung malformations (CLMs) comprise a spectrum of developmental anomalies of lung parenchyma, airways, and vasculature. CLMs are increasingly diagnosed prenatally but remain best characterized by postnatal cross-sectional imaging. During pregnancy, ultrasound (US) and fetal magnetic resonance imaging (MRI) are commonly used to monitor lung lesions. Management of CLMs, including imaging, in infants and young children depends on associated symptoms and institutional standards. Chest CT angiography (CTA) is usually the most appropriate initial postnatal imaging modality for assessing prenatally diagnosed or clinically suspected CLMs in asymptomatic infants and children. Magnetic resonance (MR) imaging/magnetic resonance angiography (MRA) may be considered as a complementary, problem-solving, imaging modality for evaluation of CLMs during fetal and neonatal periods. This article presents contemporary perspectives on the imaging approach to pediatric patients with suspected CLMs and reviews up-to-date radiologic findings and clinical characteristics of CLMs.
小儿先天性肺发育异常(CLMs)包括一系列肺实质、气道和血管的发育异常。CLMs越来越多地在产前被诊断出来,但仍以产后横断面成像为最佳特征。在孕期,超声(US)和胎儿磁共振成像(MRI)常用于监测肺部病变。婴幼儿CLMs的管理,包括成像,取决于相关症状和机构标准。胸部CT血管造影(CTA)通常是评估无症状婴幼儿产前诊断或临床怀疑的CLMs的最合适的初始产后成像方式。磁共振(MR)成像/磁共振血管造影(MRA)可被视为在胎儿和新生儿期评估CLMs的一种补充性、解决问题的成像方式。本文介绍了对疑似CLMs的小儿患者成像方法的当代观点,并回顾了CLMs的最新放射学表现和临床特征。