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开发一种集成 EEG/fNIRS 的脑功能监测系统。

Development of an Integrated EEG/fNIRS Brain Function Monitoring System.

机构信息

Biomedical Science and Engineering Department, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.

N.CER Co., Ltd., Gwangju 61005, Korea.

出版信息

Sensors (Basel). 2021 Nov 19;21(22):7703. doi: 10.3390/s21227703.

Abstract

In this study, a fully integrated electroencephalogram/functional near-infrared spectroscopy (EEG/fNIRS) brain monitoring system was designed to fulfill the demand for a miniaturized, light-weight, low-power-consumption, and low-cost brain monitoring system as a potential tool with which to screen for brain diseases. The system is based on the ADS1298IPAG Analog Front-End (AFE) and can simultaneously acquire two-channel EEG signals with a sampling rate of 250 SPS and six-channel fNIRS signals with a sampling rate of 8 SPS. AFE is controlled by Teensy 3.2 and powered by a lithium polymer battery connected to two protection circuits and regulators. The acquired EEG and fNIRS signals are monitored and stored using a Graphical User Interface (GUI). The system was evaluated by implementing several tests to verify its ability to simultaneously acquire EEG and fNIRS signals. The implemented system can acquire EEG and fNIRS signals with a CMRR of -115 dB, power consumption of 0.75 mW/ch, system weight of 70.5 g, probe weight of 3.1 g, and a total cost of USD 130. The results proved that this system can be qualified as a low-cost, light-weight, low-power-consumption, and fully integrated EEG/fNIRS brain monitoring system.

摘要

在这项研究中,设计了一种完全集成的脑电图/功能近红外光谱(EEG/fNIRS)脑监测系统,以满足对小型化、轻量化、低功耗和低成本脑监测系统的需求,作为筛查脑部疾病的潜在工具。该系统基于 ADS1298IPAG 模拟前端 (AFE),可同时以 250 SPS 的采样率采集两个通道的 EEG 信号和以 8 SPS 的采样率采集六个通道的 fNIRS 信号。AFE 由 Teensy 3.2 控制,并由连接到两个保护电路和稳压器的锂聚合物电池供电。使用图形用户界面 (GUI) 监测和存储采集到的 EEG 和 fNIRS 信号。通过实施多项测试来验证同时采集 EEG 和 fNIRS 信号的能力,对所实现的系统进行了评估。所实现的系统可以以-115 dB 的共模抑制比、0.75 mW/ch 的功耗、70.5 g 的系统重量、3.1 g 的探头重量和 130 美元的总费用来采集 EEG 和 fNIRS 信号。结果证明,该系统可以作为一种低成本、轻量化、低功耗和完全集成的 EEG/fNIRS 脑监测系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c43/8625300/aad75a6f6fb5/sensors-21-07703-g001.jpg

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