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从临床角度看可能有用的肠道微生物群参数。

Gut Microbiota Parameters Potentially Useful in Clinical Perspective.

作者信息

Di Pierro Francesco

机构信息

Digestive Endoscopy & Gastroenterology, Fondazione Poliambulanza, 25124 Brescia, Italy.

UNICAM, Camerino University, 62032 Camerino, Italy.

出版信息

Microorganisms. 2021 Nov 22;9(11):2402. doi: 10.3390/microorganisms9112402.

Abstract

Interest in gut microbiota analyses is at an all-time high. Gut microbiota is thought to relate to an increasing range of diseases of interest to physicians and nutritionists. Overweight, obesity, response to diet, metabolic syndrome, low grade inflammation, diabetes and colon neoplasms could maybe be observed in microbiota if affordable markers were available. Possible biomarkers like the Firmicutes/Bacteroidetes ratio, the Gram-positive/Gram-negative ratio, the / ratio, and the / ratio are here reviewed in a narrative way in the attempt to highlight their possible future role in routine practice and clinically relevant diagnostics.

摘要

对肠道微生物群分析的兴趣空前高涨。肠道微生物群被认为与越来越多医生和营养学家感兴趣的疾病有关。如果有价格合理的标志物,超重、肥胖、对饮食的反应、代谢综合征、低度炎症、糖尿病和结肠肿瘤可能在微生物群中被观察到。诸如厚壁菌门/拟杆菌门比率、革兰氏阳性菌/革兰氏阴性菌比率等可能的生物标志物在此以叙述方式进行综述,试图突出它们未来在常规实践和临床相关诊断中可能发挥的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2862/8623243/e5a025aad5cb/microorganisms-09-02402-g001.jpg

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