Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey CP 64710, Mexico.
Laboratorio de Endocrinologia y Nutricion, Departamento de Investigacion Biomedica, Facultad de Medicina, Universidad Autonoma de Queretaro, Queretaro CP 76176, Mexico.
Nutrients. 2021 Nov 8;13(11):3975. doi: 10.3390/nu13113975.
According to the Iodine Global Network, Mexico is considered a country with adequate national iodine intake (297 mg/L), but some regions have not been studied. We aimed to evaluate urinary iodine concentration (UIC) and its association with thyroid stimulating hormone (TSH) levels and the nutritional status in 307 children (aged 5 to 11 years) from three elementary schools of Monterrey, northern Mexico. UIC in spot urine samples and capillary TSH levels were measured to assess thyroid function, in addition to weight, height, body mass index (BMI), and waist circumference (WC). We found a median UIC of 442 mg/L and a significant association between UIC and TSH levels by logistic regression when data were adjusted for (1) age and sex; (2) age, sex, and WC; and (3) age, sex, and weight status. UIC values were higher in 7-year-old children compared to 11-year-old children. High prevalences of overweight/obesity (41%) and WC >90 pctl (22%) were observed. This study identified higher UIC levels in children than those previously reported in the country. The UIC showed a positive and significant correlation between TSH levels in the three models evaluated. More studies are needed to assess the causes and possible outcomes of high UIC levels.
根据碘全球网络的数据，墨西哥被认为是碘摄入量充足的国家（297 毫克/升），但有些地区尚未进行研究。我们旨在评估 307 名来自墨西哥北部蒙特雷的三所小学的 5 至 11 岁儿童的尿碘浓度（UIC）及其与促甲状腺激素（TSH）水平和营养状况的关系。我们测量了尿样中的 UIC 和毛细血管 TSH 水平，以评估甲状腺功能，同时还测量了体重、身高、体重指数（BMI）和腰围（WC）。我们发现，在校正（1）年龄和性别；（2）年龄、性别和 WC；以及（3）年龄、性别和体重状况后，UIC 的中位数为 442 毫克/升，UIC 与 TSH 水平之间存在显著的逻辑回归关联。7 岁儿童的 UIC 值高于 11 岁儿童。超重/肥胖（41%）和 WC >90 pctl（22%）的高患病率。本研究发现，儿童的 UIC 值高于该国之前报告的值。在评估的三个模型中，UIC 与 TSH 水平之间存在正相关且显著相关。需要进一步研究来评估高 UIC 水平的原因和可能的结果。
