Department of Pharmacognosy, Poznan University of Medical Sciences, Swiecickiego 4, 60-781 Poznań, Poland.
Department of Pharmacognosy, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
Nutrients. 2021 Nov 12;13(11):4051. doi: 10.3390/nu13114051.
Herbal infusions are an underestimated and easy to intake a source of biologically active natural compounds (polyphenols), which, in the dissolved form, are more easily absorbed. Therefore, this study aimed to assess the potential of herbal infusions as a functional food to reduce postprandial hyperglycemia (inhibition of α-amylase and α-glucosidase) and to reduce the effects of increased blood glucose level (antioxidant effect-DPPH, CUPRAC, and Fe chelating assays, as well as anti-inflammatory activity-inhibition of collagenase). We showed that polyphenols are present in the examined aqueous herbal infusions (including chlorogenic and gallic acids). Subsequently, our research has shown that herbal infusions containing cinnamon bark, mulberry leaves, and blackberry fruits most strongly inhibit glucose release from complex carbohydrates, and that all herbal infusions can, to different degrees, reduce the effects of elevated blood sugar. In conclusion, infusions prepared from herbal blends could be recommended to prevent type II diabetes.
草药浸剂是一种被低估的、易于摄入的生物活性天然化合物（多酚）来源，这些化合物以溶解形式更容易被吸收。因此，本研究旨在评估草药浸剂作为一种功能性食品的潜力，以降低餐后高血糖（抑制α-淀粉酶和α-葡萄糖苷酶）和降低血糖升高的影响（抗氧化作用-DPPH、CUPRAC 和 Fe 螯合测定，以及抗炎活性-胶原酶抑制）。我们表明，多酚存在于所检查的水性草药浸剂中（包括绿原酸和没食子酸）。随后，我们的研究表明，含有肉桂皮、桑叶和黑莓果实的草药浸剂最能抑制复杂碳水化合物中葡萄糖的释放，而且所有的草药浸剂都能在不同程度上降低血糖升高的影响。总之，由草药混合物制成的浸剂可推荐用于预防 II 型糖尿病。
