Huang Yuhong, Liu Yang, Liu Chang, Birchler James A, Han Fangpu
State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing, 100101, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
Genes Genomics. 2022 Mar;44(3):251-257. doi: 10.1007/s13258-021-01187-9. Epub 2021 Nov 27.
The advent of high-throughput epigenome mapping techniques has ushered in a new era of multiomics with powerful tools now available to map and record genomic output at different levels. Integrating the different components of the epigenome from these multiomics measures allows investigations of cis-regulatory elements on a genome-scale. Mapping of chromatin state, chromatin accessibility dynamics, and higher-order chromatin structure enables a new level of understanding of cell fate determination, identity and function in normal growth and development, disease resistance, and yield.
In this paper, the recent advances in epigenomics research of rice, maize, and wheat are reviewed, and the development trends of epigenomics of major crops in the coming years are projected.
We highlight the role of epigenomics in regulating growth and development and identifying potential distal cis-regulatory elements in three major crops, and discuss the prospects and challenges for new epigenetics-mediated breeding technologies in crop improvement.
In this review, we summarize and analyze recent epigenomic advances in three major crops epigenomics and discuss possibilities and challenges for future research in the field.
高通量表观基因组图谱技术的出现开启了多组学的新时代，现在有了强大的工具来在不同水平上绘制和记录基因组输出。整合来自这些多组学测量的表观基因组的不同组成部分，能够在全基因组范围内研究顺式调控元件。染色质状态、染色质可及性动态变化以及高阶染色质结构的图谱绘制，使人们对细胞命运决定、正常生长发育、抗病性和产量中的细胞身份及功能有了新的认识。
本文综述了水稻、玉米和小麦表观基因组学研究的最新进展，并预测了未来几年主要作物表观基因组学的发展趋势。
我们强调了表观基因组学在调控三种主要作物生长发育以及鉴定潜在远端顺式调控元件方面的作用，并讨论了新的表观遗传学介导的育种技术在作物改良中的前景和挑战。
在本综述中，我们总结并分析了三种主要作物表观基因组学的最新进展，并讨论了该领域未来研究的可能性和挑战。
