School of Public Health, WeiFang Medical University, Weifang, 261053, China.
Tianjin International Joint Academy of Biomedicine, Tianjin, 300457, China.
Virol J. 2021 Nov 27;18(1):233. doi: 10.1186/s12985-021-01704-y.
Dabieshan tick virus (DTV) was first identified in Haemaphysalis longicornis from Hubei Province, China in 2015. However, its pathogenic potential to animals and human remains to be further explored. In this study, a total of 170 engorged ticks and 22 sheep serum samples were collected from Taian and Yantai city, Shandong Province to investigate the presence of DTV. The results of qRT-PCR revealed the positive rate of 13.6% (3/22) in sheep serum and 8.2% (14/170) in attached ticks, respectively. Phylogenetic analysis demonstrated a close evolutionary relationship among those DTV isolates from animal and ticks, and DTV might be relatively conservative in evolution. These findings are the first to demonstrate molecular evidence of DTV in domestic animals. Nonetheless, whether or not causing disease in animals, DTV deserves further investigation.
大别山 tick 病毒（DTV）于 2015 年在中国湖北省首次从长角血蜱中鉴定出来。然而，其对动物和人类的致病潜力仍有待进一步探索。本研究共采集了来自山东省泰安市和烟台市的 170 只饱血蜱和 22 份绵羊血清样本，以调查 DTV 的存在情况。qRT-PCR 的结果显示，绵羊血清的阳性率为 13.6%（22 份中的 3 份），附着蜱的阳性率为 8.2%（170 只中的 14 只）。系统进化分析表明，来自动物和蜱的 DTV 分离株之间存在密切的进化关系，DTV 在进化过程中可能相对保守。这些发现首次证明了 DTV 在家畜中的分子证据。尽管 DTV 是否会导致动物患病仍有待进一步调查，但它值得进一步研究。
