Department of Pediatrics, School of Medicine, Children and Adolescents Health Research Center, Ali-Ibn-Abitaleb Hospital, Zahedan, Iran.
Department of Pediatrics, Ali-ebne-Abitaleb Hospital, Zehedan University of Medical Sciences, Zahedan, Iran.
Antimicrob Resist Infect Control. 2021 Nov 27;10(1):165. doi: 10.1186/s13756-021-01020-8.
Even though children seem to be less vulnerable to the Coronavirus disease 2019 (COVID-19) infection, still a diverse range of clinical presentations and symptoms have been reported in children. Few studies assessed the clinical presentations of COVID-19 among Iranian children. We aimed to evaluate the clinical and paraclinical characteristics of COVID-19 infected children.
All COVID-19 suspected and confirmed children were referred to the Ali-ibn-Abitaleb Hospital, Zahedan, Iran. Patients were included in this longitudinal study. Patients were evaluated at admission and during hospitalization. Patients with some of the main COVID symptoms with positive PCR test were defined as confirmed cases. Clinical, imaging and laboratory results were collected for all patients.
A total of 62 patients participated in this study. The male:female ratio was 1:1.03. There was a significant difference in fatigue prevalence between age groups (P = 0.002). There was no significant difference between groups in terms of fever duration (P = 0.624) and maximum temperature (P = 0.629). There was a significant difference between PCR positive and negative patients in terms of neurologic signs (P = 0.003), Intensive care unit admission (P = 0.001), white blood cell (P = 0.047).
Even though our population was small, most of the findings matched other studies conducted on pediatric cases in Iran or other countries. It was also found that some clinical features such as pneumonia, cough, diarrhea, and tachycardia at admission time were statistically different among age groups.
尽管儿童似乎不易感染 2019 年冠状病毒病（COVID-19），但仍有多种临床表现和症状在儿童中报告。少数研究评估了伊朗儿童 COVID-19 的临床表现。我们旨在评估 COVID-19 感染儿童的临床和辅助检查特征。
所有 COVID-19 疑似和确诊儿童均被转诊至伊朗扎黑丹的阿里·伊本·阿比·塔利卜医院。患者被纳入本纵向研究。患者在入院时和住院期间进行评估。将具有某些主要 COVID 症状且 PCR 检测呈阳性的患者定义为确诊病例。所有患者均收集临床、影像学和实验室结果。
共有 62 名患者参与了这项研究。男女比例为 1:1.03。不同年龄组之间疲劳发生率存在显著差异（P=0.002）。发热持续时间（P=0.624）和最高体温（P=0.629）在组间无显著差异。PCR 阳性和阴性患者在神经系统体征（P=0.003）、重症监护病房入院（P=0.001）、白细胞计数（P=0.047）方面存在显著差异。
尽管我们的样本量较小，但大多数发现与伊朗或其他国家开展的儿科病例研究相吻合。此外，还发现一些临床特征，如入院时的肺炎、咳嗽、腹泻和心动过速，在不同年龄组之间存在统计学差异。
