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对于伴有浸润性癌的胆囊导管内乳头状肿瘤破裂患者,采取根治性意图的根治性胆囊切除术,随后进行腹腔内热化疗。

Curative intent radical cholecystectomy followed by hyperthermic intraperitoneal chemotherapy in ruptured intraductal papillary neoplasm of gallbladder with invasive carcinoma.

作者信息

Choi Gyeonggyu, Jang Seokwon, Choi Munseok, Yang Seungyoon, Lee Chunggeun, Kang Chang Moo

机构信息

Yonsei University College of Medicine, Seoul, Korea.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Ann Hepatobiliary Pancreat Surg. 2022 Feb 28;26(1):113-117. doi: 10.14701/ahbps.21-071.

DOI:10.14701/ahbps.21-071
PMID:34840144
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8901977/
Abstract

Gallbladder cancer has a poor prognosis, especially in peritoneal carcinomatosis related to perforation of the gallbladder followed by bile spillage. Previously, curative-intent treatment was not considered in carcinomatosis from cancer of the biliary tract. A 72-year-old male was referred to the hospital with a perforated gallbladder cancer. Intraoperatively, the tumor was confined to the gallbladder and liver. We presented a case of intention-to-curative resection of perforated gallbladder cancer followed by intraoperative hyperthermic intraperitoneal chemotherapy.

摘要

胆囊癌预后较差,尤其是在与胆囊穿孔及胆汁外溢相关的腹膜种植转移时。此前,对于胆道系统癌症的腹膜种植转移,未考虑进行根治性治疗。一名72岁男性因胆囊穿孔性癌被转诊至我院。术中发现肿瘤局限于胆囊和肝脏。我们报告了一例对穿孔性胆囊癌进行根治性切除并术中进行腹腔内热化疗的病例。

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Curative intent radical cholecystectomy followed by hyperthermic intraperitoneal chemotherapy in ruptured intraductal papillary neoplasm of gallbladder with invasive carcinoma.对于伴有浸润性癌的胆囊导管内乳头状肿瘤破裂患者,采取根治性意图的根治性胆囊切除术,随后进行腹腔内热化疗。
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2
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Is cytoreductive surgery and hyperthermic intraperitoneal chemotherapy indicated in hepatobiliary malignancies?细胞减灭术和腹腔内热灌注化疗是否适用于肝胆恶性肿瘤?
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本文引用的文献

1
Role of postoperative adjuvant therapy in resected invasive intraductal papillary mucinous neoplasm of the pancreas: A multicenter external validation.术后辅助治疗在胰腺切除的浸润性导管内乳头状黏液性肿瘤中的作用:多中心外部验证
J Hepatobiliary Pancreat Sci. 2021 Aug;28(8):671-679. doi: 10.1002/jhbp.996. Epub 2021 Jun 14.
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Role of tumour location and surgical extent on prognosis in T2 gallbladder cancer: an international multicentre study.肿瘤位置和手术范围对 T2 期胆囊癌预后的作用:一项国际多中心研究。
Br J Surg. 2020 Sep;107(10):1334-1343. doi: 10.1002/bjs.11618. Epub 2020 May 26.
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Oncologic safety of laparoscopic radical cholecystectomy in pT2 gallbladder cancer: A propensity score matching analysis compared to open approach.
Cytoreductive Surgery and HIPEC for Regionally Advanced Gallbladder Cancer: a Case Report.
减瘤手术与热灌注化疗治疗局部晚期胆囊癌:一例报告
Indian J Surg Oncol. 2023 Jun;14(Suppl 1):127-130. doi: 10.1007/s13193-022-01634-3. Epub 2022 Aug 29.
pT2期胆囊癌腹腔镜根治性胆囊切除术的肿瘤学安全性:与开放手术对比的倾向评分匹配分析
Medicine (Baltimore). 2020 May;99(20):e20039. doi: 10.1097/MD.0000000000020039.
4
Long-term outcomes of surgical resection for T1b gallbladder cancer: an institutional evaluation.T1b 期胆囊癌行手术切除的长期疗效:一项机构评估。
BMC Cancer. 2020 Jan 6;20(1):20. doi: 10.1186/s12885-019-6507-2.
5
Characterization of Intraductal Papillary Neoplasm of the Bile Duct with Respect to the Histopathologic Similarities to Pancreatic Intraductal Papillary Mucinous Neoplasm.胆管内乳头状肿瘤的组织病理学特征与胰腺内乳头状黏液性肿瘤的相似性。
Gut Liver. 2019 Nov 15;13(6):617-627. doi: 10.5009/gnl18476.
6
Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer.腹腔内热灌注化疗治疗卵巢癌。
N Engl J Med. 2018 Jan 18;378(3):230-240. doi: 10.1056/NEJMoa1708618.
7
Gallbladder Cancer: Complete Resection after Second Line Treatment in Stage IV Disease.胆囊癌:IV期疾病二线治疗后行根治性切除术
J Gastrointest Cancer. 2019 Sep;50(3):564-567. doi: 10.1007/s12029-017-0044-5.
8
Conditional survival in patients with gallbladder cancer.胆囊癌患者的条件生存情况。
Chin J Cancer. 2017 Oct 30;36(1):85. doi: 10.1186/s40880-017-0252-1.
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Long-term survival after multidisciplinary therapy for residual gallbladder cancer with peritoneal dissemination: a case report.多学科治疗残余胆囊癌伴腹膜播散后的长期生存:一例报告
Surg Case Rep. 2017 Dec;3(1):76. doi: 10.1186/s40792-017-0351-x. Epub 2017 Jun 14.
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Complete cytoreductive surgery plus HIPEC for peritoneal metastases from unusual cancer sites of origin: results from a worldwide analysis issue of the Peritoneal Surface Oncology Group International (PSOGI).完整的细胞减灭术联合 HIPEC 治疗源自罕见部位的腹膜转移癌:腹膜表面肿瘤国际协会(PSOGI)的全球分析结果。
Int J Hyperthermia. 2017 Aug;33(5):520-527. doi: 10.1080/02656736.2017.1301576.