Wade Martin, Charest Vanessa, Ballardin Bruno, Edge Deirdre, Nielsen Michael Canova Engelbrecht
Dr. Wade, Ms. Charest, and Mr. Ballardin are with the London Skin and Hair Clinic in London, England.
Drs. Edge and Nielsen are with Guangdong Klox Biomedical Group Co., Ltd., in Guangzhou, China.
J Clin Aesthet Dermatol. 2021 Jul;14(7):16-21. Epub 2021 Jul 1.
Rosacea is a difficult-to-manage chronic inflammatory skin condition reported to have a negative psychosocial impact on patients. Novel approaches are sought to target the many signs and symptoms of the condition while also improving the quality of life of patients.
We assessed the efficacy of the Kleresca biophotonic platform (KLOX Technologies Inc., Laval, Canada), which creates fluorescent light energy (FLE), to induce a novel form of photobiomodulation for treating rosacea. We also assessed patient satisfaction with their facial appearance and concerns about perceptions of others before and after treatment.
Nine patients were treated once a week for four weeks with FLE. Patients and the treating clinician completed questionnaires throughout and after the treatment to grade the rosacea signs and symptoms and capture patients' perceptions of the treatment and their condition.
FLE significantly reduced the inflammatory erythematous reaction of the face, improved flushing and erythema associated with rosacea, and had a positive impact on patients' self-perception and emotional wellbeing.
Our results support FLE as an effective, noninvasive treatment modality for rosacea.
酒渣鼻是一种难以管理的慢性炎症性皮肤病，据报道会对患者产生负面的心理社会影响。人们正在寻求新的方法来针对该病的多种体征和症状，同时提高患者的生活质量。
我们评估了Kleresca生物光子平台（加拿大拉瓦尔的KLOX Technologies Inc.）产生荧光光能（FLE）以诱导一种新型光生物调节疗法治疗酒渣鼻的疗效。我们还评估了患者在治疗前后对其面部外观的满意度以及对他人看法的担忧。
9名患者每周接受一次FLE治疗，共治疗四周。患者和主治医生在治疗期间及治疗后完成问卷，以对酒渣鼻的体征和症状进行评分，并了解患者对治疗及其病情的看法。
FLE显著减轻了面部的炎症性红斑反应，改善了与酒渣鼻相关的潮红和红斑，并对患者的自我认知和情绪健康产生了积极影响。
我们的结果支持FLE作为一种治疗酒渣鼻的有效、非侵入性治疗方式。
