Copenhagen Research Group for Inflammatory Skin (CORGIS), Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Kildegaardsvej 28, 2900, Hellerup, Denmark.
Br J Dermatol. 2018 Aug;179(2):282-289. doi: 10.1111/bjd.16481. Epub 2018 May 31.
The exact prevalence and incidence of rosacea remain unknown, although it is a common condition associated with severe noncutaneous diseases.
To perform a systematic review of the published literature to examine the global incidence and prevalence of rosacea.
A systematic review of population-based and dermatological outpatient studies reporting the incidence and/or prevalence of rosacea was performed using three electronic medical databases: PubMed, Embase and Web of Science. Data were extracted and a proportion meta-analysis was performed to obtain pooled proportions.
In total 32 studies were included examining a total of 41 populations with 26 519 836 individuals. Twenty-two populations were from Europe, three from Africa, four from Asia, nine from North America and three from South America. The pooled proportion of individuals with rosacea was 5·46% [95% confidence interval (CI) 4·91-6·04] in the general population and 2·39% (95% CI 1·56-3·39) among dermatological outpatients. Self-reported rosacea gave higher prevalence estimates than rosacea diagnosed by clinical examination, suggesting a low specificity of questionnaires based on symptoms. Rosacea affected both women (5·41%, 95% CI 3·85-7·23) and men (3·90%, 95% CI 3·04-4·87), and mostly those aged 45-60 years.
We estimated the global prevalence of rosacea based on published data and found that 5·46% of the adult population is affected. However, the prevalence of rosacea depended on the diagnostic method, with higher estimates in questionnaire studies of rosacea symptoms and lower estimates in health registries with International Classification of Diseases codes.
尽管酒渣鼻是一种与严重非皮肤疾病相关的常见病症，但确切的患病率和发病率仍不清楚。
对已发表的文献进行系统回顾，以检查酒渣鼻的全球发病率和患病率。
使用三个电子医学数据库（PubMed、Embase 和 Web of Science）对报告酒渣鼻发病率和/或患病率的基于人群和皮肤科门诊的研究进行了系统回顾。提取数据并进行比例荟萃分析以获得汇总比例。
共纳入 32 项研究，共涉及 41 个人群，共 26519836 人。22 个人群来自欧洲，3 个人群来自非洲，4 个人群来自亚洲，9 个人群来自北美，3 个人群来自南美。普通人群中酒渣鼻患者的比例为 5.46%（95%置信区间 4.91-6.04），皮肤科门诊患者中酒渣鼻患者的比例为 2.39%（95%置信区间 1.56-3.39）。自我报告的酒渣鼻患病率高于临床检查诊断的酒渣鼻患病率，这表明基于症状的问卷特异性较低。酒渣鼻影响女性（5.41%，95%置信区间 3.85-7.23）和男性（3.90%，95%置信区间 3.04-4.87），主要影响 45-60 岁的人群。
我们根据已发表的数据估计了全球酒渣鼻的患病率，发现 5.46%的成年人口受到影响。然而，酒渣鼻的患病率取决于诊断方法，在基于酒渣鼻症状的问卷调查研究中患病率较高，而在使用国际疾病分类代码的健康登记中患病率较低。
