Muhsen Baha'eddin A, Ghzawi Ansam, Fares Ahmad Salah, Al-Hussaini Maysa, Salah Samer
Department of Surgery, Division of Neurosurgery, King Hussein Cancer Center, Amman, Jordan.
Faculty of Medicine, Yarmouk University, Irbid, Jordan.
Future Sci OA. 2021 Oct 25;7(10):FSO756. doi: 10.2144/fsoa-2021-0077. eCollection 2021 Dec.
Myxoid liposarcoma (MLS) is a rare malignant soft-tissue neoplasm in which brain metastasis is still considered rare. We present a case of MLS brain metastasis and review of the literature.
A 24-year-old male patient presented with headache, decreased level of consciousness and vomiting. He was treated for distal right thigh MLS 2-years ago. Imaging studies of the brain showed a left frontal intracranial mass. The patient underwent surgical resection followed by stereotactic radiosurgery. The histopathological study revealed metastatic myxoid/roundcell liposarcoma infiltrating the bone and peripheral margins.
Treatment options for MLS usually includes surgical resection and adjuvant radiotherapy. A case-by-case based multidisciplinary approach is recommended for the management of similar cases.
黏液样脂肪肉瘤(MLS)是一种罕见的恶性软组织肿瘤,脑转移仍被认为较为罕见。我们报告一例MLS脑转移病例并进行文献复习。
一名24岁男性患者出现头痛、意识水平下降和呕吐症状。他在2年前因右大腿远端MLS接受过治疗。脑部影像学检查显示左额叶颅内肿块。患者接受了手术切除,随后进行了立体定向放射外科治疗。组织病理学研究显示转移性黏液样/圆形细胞脂肪肉瘤浸润骨骼和周边边缘。
MLS的治疗选择通常包括手术切除和辅助放疗。对于类似病例的管理,建议采用基于个案的多学科方法。