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脑转移性黏液样脂肪肉瘤:一例报告并文献复习

Metastatic myxoid liposarcoma of the brain: a case report and review of the literature.

作者信息

Muhsen Baha'eddin A, Ghzawi Ansam, Fares Ahmad Salah, Al-Hussaini Maysa, Salah Samer

机构信息

Department of Surgery, Division of Neurosurgery, King Hussein Cancer Center, Amman, Jordan.

Faculty of Medicine, Yarmouk University, Irbid, Jordan.

出版信息

Future Sci OA. 2021 Oct 25;7(10):FSO756. doi: 10.2144/fsoa-2021-0077. eCollection 2021 Dec.

Abstract

AIM

Myxoid liposarcoma (MLS) is a rare malignant soft-tissue neoplasm in which brain metastasis is still considered rare. We present a case of MLS brain metastasis and review of the literature.

CASE PRESENTATION

A 24-year-old male patient presented with headache, decreased level of consciousness and vomiting. He was treated for distal right thigh MLS 2-years ago. Imaging studies of the brain showed a left frontal intracranial mass. The patient underwent surgical resection followed by stereotactic radiosurgery. The histopathological study revealed metastatic myxoid/roundcell liposarcoma infiltrating the bone and peripheral margins.

CONCLUSION

Treatment options for MLS usually includes surgical resection and adjuvant radiotherapy. A case-by-case based multidisciplinary approach is recommended for the management of similar cases.

摘要

目的

黏液样脂肪肉瘤(MLS)是一种罕见的恶性软组织肿瘤,脑转移仍被认为较为罕见。我们报告一例MLS脑转移病例并进行文献复习。

病例介绍

一名24岁男性患者出现头痛、意识水平下降和呕吐症状。他在2年前因右大腿远端MLS接受过治疗。脑部影像学检查显示左额叶颅内肿块。患者接受了手术切除,随后进行了立体定向放射外科治疗。组织病理学研究显示转移性黏液样/圆形细胞脂肪肉瘤浸润骨骼和周边边缘。

结论

MLS的治疗选择通常包括手术切除和辅助放疗。对于类似病例的管理,建议采用基于个案的多学科方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65d9/8610000/3a9dde12b673/fsoa-07-756-g1.jpg

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