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COVID-19 流行病学:一年来发生了哪些变化?

Epidemiology of COVID-19: What changed in one year?

机构信息

Department of Infectious Diseases & Clinical Microbiology, Faculty of Medicine, Health Science University, Ankara, Turkey

School of Medicine, International University of Health and Welfare, Narita, Japan

出版信息

Turk J Med Sci. 2021 Dec 17;51(SI-1):3253-3261. doi: 10.3906/sag-2110-153.

DOI:10.3906/sag-2110-153
PMID:34844297
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8771048/
Abstract

A coronavirus brought the first pandemic attack of this century as a flu virus did a hundred years ago. This greatest pandemic of the century brings us new opportunities to understand and explore the dynamics of a contagious disease. Nearly two years later, we are still collecting the evidence to understand the disease. Some basic epidemiological properties are still urgently needed. Not only the origin of the virus but also Ro value, possible transmission routes, epidemiologic curves, case fatality rates, seasonality, severity and mortality risk factor, effects on the risk groups, differences between countries and so on still require strong evidence prior to making final suggestions. In this review, we tried to evaluate the epidemiological evidence to scrutinize where exactly we are in this pandemic.

摘要

一种冠状病毒引发了本世纪的首次大流行,就像 100 年前流感病毒引发的大流行一样。本世纪最大的这场大流行使我们有机会深入了解和探索传染病的动态。将近两年过去了,我们仍在收集证据以了解这种疾病。一些基本的流行病学特性仍迫切需要。不仅需要病毒的起源,还需要 Ro 值、可能的传播途径、流行病学曲线、病死率、季节性、严重程度和死亡风险因素、对高危人群的影响、国家之间的差异等方面的强证据,然后才能提出最终建议。在这篇综述中,我们试图评估流行病学证据,仔细审视我们在这场大流行中的位置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/e1430bc26de1/turkjmedsci-51-3253-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/a40b512503ed/turkjmedsci-51-3253-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/a96e34a9cd65/turkjmedsci-51-3253-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/65367fa41074/turkjmedsci-51-3253-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/e1430bc26de1/turkjmedsci-51-3253-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/a40b512503ed/turkjmedsci-51-3253-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/a96e34a9cd65/turkjmedsci-51-3253-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/65367fa41074/turkjmedsci-51-3253-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac03/8771048/e1430bc26de1/turkjmedsci-51-3253-fig004.jpg

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Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01.HLA-C*04:01携带者感染新型冠状病毒肺炎后出现严重临床病程的风险增加。
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Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses.鉴定新型蝙蝠冠状病毒有助于了解 SARS-CoV-2 及相关病毒的进化起源。
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