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Arch Med Res. 2021 Feb;52(2):240-241. doi: 10.1016/j.arcmed.2020.10.012. Epub 2020 Oct 17.
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本文引用的文献

1
Increased Risk of Hospitalization and Death in Patients with COVID-19 and Pre-existing Noncommunicable Diseases and Modifiable Risk Factors in Mexico.墨西哥患有 COVID-19 及既往非传染性疾病和可改变的危险因素的患者住院和死亡风险增加。
Arch Med Res. 2020 Oct;51(7):683-689. doi: 10.1016/j.arcmed.2020.07.003. Epub 2020 Jul 22.
2
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19.SARS-CoV-2 反应性 T 细胞在健康供体和 COVID-19 患者中的研究。
Nature. 2020 Nov;587(7833):270-274. doi: 10.1038/s41586-020-2598-9. Epub 2020 Jul 29.
3
Pre-existing immunity to SARS-CoV-2: the knowns and unknowns.SARS-CoV-2 预先存在的免疫力:已知和未知。
Nat Rev Immunol. 2020 Aug;20(8):457-458. doi: 10.1038/s41577-020-0389-z.
4
Obesity and COVID-19: The mTOR pathway as a possible culprit.肥胖与2019冠状病毒病:mTOR信号通路或为潜在罪魁祸首。
Obes Rev. 2020 Sep;21(9):e13084. doi: 10.1111/obr.13084. Epub 2020 Jun 23.
5
The epidemiology and clinical impact of pandemic influenza.大流行性流感的流行病学及临床影响。
Vaccine. 2003 May 1;21(16):1762-8. doi: 10.1016/s0264-410x(03)00069-0.
6
Emerging infections: pandemic influenza.新发传染病:大流行性流感
Epidemiol Rev. 1996;18(1):64-76. doi: 10.1093/oxfordjournals.epirev.a017917.

新冠病毒和流感大流行遵循一种模式:大流行起源地可能存在交叉免疫力,而在更远的地区则会出现更严重的疾病。

COVID-19 and Flu Pandemics Follow a Pattern: A Possible Cross-immunity in the Pandemic Origin and Graver Disease in Farther Regions.

机构信息

College of Pharmacy, Oregon State University, Corvallis, Oregon, USA.

Department of Health Care Administration and Policy, School of Public Health, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.

出版信息

Arch Med Res. 2021 Feb;52(2):240-241. doi: 10.1016/j.arcmed.2020.10.012. Epub 2020 Oct 17.

DOI:10.1016/j.arcmed.2020.10.012
PMID:33645503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7568123/
Abstract

So far, the COVID-19 pandemic has caused less casualty in Eastern Asia areas compared to the other parts of the world. The pattern of less casualty in the pandemic origin has also been observed in the three main flu pandemics in the last century. It is reasonable to speculate that less casualty of COVID-19/flu in the pandemic origin is likely due to the preexisting cross-immunity to some close viruses being more prevalent in those regions. Experts and modelers should scale up the severity of a flu-like viral epidemic to predict its real severity for the rest of the world.

摘要

到目前为止,与世界其他地区相比,东亚地区的 COVID-19 大流行造成的死亡人数较少。在上个世纪的三次主要流感大流行中,也观察到了这种大流行起源地死亡人数较少的模式。因此,可以合理推测,COVID-19/流感在大流行起源地造成的死亡人数较少,可能是由于这些地区更普遍存在对一些密切相关病毒的交叉免疫。专家和建模者应该加大类似流感的病毒性流行的严重程度,以预测其对世界其他地区的实际严重程度。