Universidade Federal de Minas Gerais (UFMG), Programa de Otorrinolaringologia, Belo Horizonte, MG, Brazil.
Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl 5(Suppl 5):S57-S62. doi: 10.1016/j.bjorl.2021.09.009. Epub 2021 Nov 10.
To highlight the prevalence of respiratory epithelial adenomatoid hamartomas in the olfactory cleft of patients with nasal polyposis. To demonstrate characteristics indicative of hamartoma on the CT scans of paranasal sinuses during surgery and in histopathological exams.
Cross-sectional study carried out in Hospital das Clínicas da UFMG and Núcleo de Otorrino BH. We performed 114 nasal endoscopic surgeries for polyposis, between February 2015 and November 2019. We assessed the olfactory cleft width in all preoperative CT scans. Upon seeing an indication of hamartoma on the CT scan, we took a tissue sample from the olfactory cleft during the surgery and sent for histopathological exam. We referred the samples to a pathologist experienced in the anatomopathological diagnosis of respiratory epithelial adenomatoid hamartomas.
Of the 114 patients with polyposis, 54 (47.4%) had olfactory cleft enlargement and, 100% of them had tissue with a dense and hardened polypoid aspect, with a slight cerebriform appearance in this region during the surgery. Histology confirmed a respiratory epithelial adenomatoid hamartoma.
This observation suggests that the presence of hamartomas in polyposis is common, but underdiagnosed.
Step 3 (Level 3).
强调在鼻息肉患者的嗅裂中存在呼吸道上皮腺瘤样错构瘤。展示在鼻窦 CT 扫描和手术中的组织病理学检查中提示错构瘤的特征。
这是在 UFMG 临床医院和 BH 耳鼻喉科核医学中心进行的横断面研究。我们对 2015 年 2 月至 2019 年 11 月期间进行的 114 例鼻息肉鼻内镜手术进行了评估。我们评估了所有术前 CT 扫描中的嗅裂宽度。在 CT 扫描上看到错构瘤的迹象时，我们会在手术期间从嗅裂中取组织样本并进行组织病理学检查。我们将样本提交给一位在呼吸上皮腺瘤样错构瘤的解剖病理诊断方面经验丰富的病理学家。
在 114 例鼻息肉患者中，54 例（47.4%）嗅裂扩大，且在手术中，所有患者均在该区域有致密且硬化的息肉样外观，有轻微的脑回状外观。组织学证实为呼吸道上皮腺瘤样错构瘤。
这一观察结果表明，鼻息肉中存在错构瘤是常见的，但诊断不足。
第 3 步（3 级）。
