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年轻亚裔男性腰椎淀粉样变性脊柱手术的麻醉挑战。

Anaesthetic challenges in the spine surgery of a young Asian man with lumbar amyloidosis.

机构信息

Anaesthesia and Intensive Care Unit, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia.

Department of Paediatrics, Melaka General Hospital, Melaka, Malaysia.

出版信息

BMJ Case Rep. 2021 Nov 29;14(11):e246359. doi: 10.1136/bcr-2021-246359.

Abstract

Primary amyloidosis is a rare systemic disorder often associated with multiple organ dysfunction. The most common form, light chain amyloidosis, has an estimated age-adjusted incidence of 5.1-12.8 cases per million person-years. Spine involvement is extremely uncommon. We present the case of a young Asian man with newly diagnosed amyloidosis involving the lumbar spine among multiple organs with a pathological vertebral fracture that required urgent spine surgery. We believe this is the first reported case to discuss the perianaesthetic challenges in the management of lumbar spine amyloidosis.

摘要

原发性淀粉样变是一种罕见的全身性疾病,常伴有多个器官功能障碍。最常见的类型是轻链淀粉样变,其年龄调整发病率估计为每百万人口每年 5.1-12.8 例。脊柱受累极为罕见。我们报告了一例年轻的亚裔男性,他患有新诊断的淀粉样变,累及多个器官,包括腰椎,并有病理性椎体骨折,需要紧急脊柱手术。我们认为这是首例报告讨论腰椎淀粉样变围手术期管理中的麻醉挑战的病例。

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