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非医用大麻使用:使用模式和相关因素、暴露和危害,以及癌症风险。

Nonmedical Cannabis Use: Patterns and Correlates of Use, Exposure, and Harm, and Cancer Risk.

机构信息

TSET Health Promotion Research Center, University of Oklahoma Health Sciences Center, Stephenson Center, Oklahoma City, OK, USA.

Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

出版信息

J Natl Cancer Inst Monogr. 2021 Nov 28;2021(58):53-67. doi: 10.1093/jncimonographs/lgab006.

Abstract

Cannabis has certain health benefits, but some people may experience harms from use. Co-use of tobacco and cannabis is common. Smoke from cannabis contains many of the same carcinogens and toxicants as the smoke from tobacco, raising concerns that cannabis smoking may be a risk factor for cancer. With growing access to and acceptance of medical and nonmedical cannabis, there is an urgent need to understand the risks and benefits of the current modes of cannabis use and how cannabis may be associated with cancer risk. This monograph summarizes a session from a National Cancer Institute Symposium on nonmedical cannabis use and cancer risk. We had 3 objectives: describe the relation between nonmedical cannabis use and cancer risk, delineate patterns and correlates of cannabis co-use with tobacco, and document potentially harmful inhalational exposure resulting from smoked and vaped cannabis. Methodological limitations in the literature and future research recommendations are provided.

摘要

大麻具有一定的健康益处,但有些人可能会因使用而受到伤害。烟草和大麻的共同使用很常见。大麻烟雾中含有许多与烟草烟雾相同的致癌物质和有毒物质,这让人担心吸食大麻可能是癌症的一个风险因素。随着人们越来越多地获得和接受医用和非医用大麻,迫切需要了解当前大麻使用模式的风险和益处,以及大麻如何与癌症风险相关。本专论总结了美国国立癌症研究所关于非医用大麻使用和癌症风险专题研讨会的一个分会场内容。我们有 3 个目标:描述非医用大麻使用与癌症风险之间的关系,描述大麻与烟草共同使用的模式和相关因素,以及记录吸食和蒸发大麻所导致的潜在有害吸入暴露。文中还提供了文献中的方法学限制和未来研究建议。

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