Paediatric Cardiology Unit, Department of Paediatrics, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria; Department of Paediatrics and Child Health, Obafemi Awolowo University, Ile-Ife, Nigeria.
Paediatric Cardiology Unit, Department of Paediatrics, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Cardiovasc J Afr. 2022;33(3):122-126. doi: 10.5830/CVJA-2021-048. Epub 2021 Nov 22.
Tetralogy of Fallot (TOF) is the leading cyanotic congenital heart disease. We commenced open-heart surgery at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria in 2016.
To review the incidence, pattern, management and treatment outcomes of TOF at the OAUTHC.
A retrospective audit was undertaken of hospital records, including echocardiograms of patients with TOF seen from January 2016 to February 2020 at the Paediatric Cardiology Unit, OAUTHC.
Seventy-two patients (37 boys and 35 girls) aged 0.17-22 years had TOF. Thirty-three (45.8%) had surgery; 31 (93.9%) corrective surgery and two (6.1%) a modified Blalock-Taussig shunt. Complications following surgery included cardiac dysfunction, post-transfusion malaria, pulmonary regurgitation, pericardial effusion and death (15%). Thirty-nine (54.2%) patients had conservative medical management. Complications included polycythaemia and thrombotic stroke, and 14 (35.9%) patients died.
TOF is associated with significant morbidity and mortality in developing countries. Early and safe corrective surgery is desirable.
法洛四联症（TOF）是最常见的发绀性先天性心脏病。我们于 2016 年在尼日利亚伊费奥巴费米·阿沃洛沃大学教学医院（OAUTHC）开始进行心脏直视手术。
回顾 OAUTHC 法洛四联症的发病率、模式、管理和治疗结果。
对 2016 年 1 月至 2020 年 2 月在 OAUTHC 儿科心脏病学系就诊的 TOF 患者的医院记录（包括超声心动图）进行回顾性审核。
72 名年龄在 0.17-22 岁的患者（37 名男孩和 35 名女孩）患有 TOF。其中 33 名（45.8%）接受了手术治疗；31 名（93.9%）行矫正手术，2 名（6.1%）行改良 Blalock-Taussig 分流术。手术后并发症包括心功能障碍、输血后疟疾、肺动脉瓣反流、心包积液和死亡（15%）。39 名（54.2%）患者接受了保守的药物治疗。并发症包括红细胞增多症和血栓性中风，14 名（35.9%）患者死亡。
TOF 在发展中国家与较高的发病率和死亡率相关。早期和安全的矫正手术是理想的。
Zotero 插件