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肌肉骨骼介入治疗:膝动脉栓塞术综述

Musculoskeletal Interventions: A Review on Genicular Artery Embolization.

作者信息

Sajan Abin, Bagla Sandeep, Isaacson Ari

机构信息

Department of Radiology, Columbia University Irving Medical Center, New York, New York.

Vascular Interventional Partners - NOVA, Falls Church, Virginia.

出版信息

Semin Intervent Radiol. 2021 Nov 24;38(5):511-514. doi: 10.1055/s-0041-1736529. eCollection 2021 Dec.

Abstract

Symptomatic knee pain is one of the most common joint diseases that affects millions of people worldwide. The treatment for knee pain secondary to osteoarthritis (OA) begins with conservative therapy and progresses to surgical intervention when conservative therapy fails. Genicular artery embolization (GAE) offers an alternative option for patients who are poor surgical candidates. Multiple studies have been conducted worldwide demonstrating the safety and efficacy of GAE in patients with mild to moderate OA. The purpose of this article is to describe the current literature on GAE and highlight the latest findings from a randomized controlled trial comparing GAE versus sham embolization.

摘要

症状性膝关节疼痛是影响全球数百万人的最常见关节疾病之一。骨关节炎(OA)继发的膝关节疼痛治疗始于保守治疗,当保守治疗失败时进展为手术干预。膝动脉栓塞术(GAE)为手术候选不佳的患者提供了一种替代选择。全球已进行多项研究,证明GAE对轻至中度OA患者的安全性和有效性。本文的目的是描述关于GAE的当前文献,并强调一项比较GAE与假栓塞术的随机对照试验的最新发现。

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本文引用的文献

1
Multicenter Randomized Sham Controlled Study of Genicular Artery Embolization for Knee Pain Secondary to Osteoarthritis.
J Vasc Interv Radiol. 2022 Jan;33(1):2-10.e2. doi: 10.1016/j.jvir.2021.09.019. Epub 2021 Oct 2.
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Genicular artEry embolizatioN in patiEnts with oSteoarthrItiS of the Knee (GENESIS) Using Permanent Microspheres: Interim Analysis.
Cardiovasc Intervent Radiol. 2021 Jun;44(6):931-940. doi: 10.1007/s00270-020-02764-3. Epub 2021 Jan 20.
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Non-neoplastic Disease Outside the Spine-Genicular Artery Embolization and Adhesive Capsulitis Embolization.
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Clinical Outcomes of Transcatheter Arterial Embolisation for Chronic Knee Pain: Mild-to-Moderate Versus Severe Knee Osteoarthritis.
Cardiovasc Intervent Radiol. 2019 Nov;42(11):1530-1536. doi: 10.1007/s00270-019-02289-4. Epub 2019 Jul 23.
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