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丙烯酸泄漏事故吸入和食入暴露的急性和慢性健康风险评估。

Acute and chronic health risk assessment for inhalation and ingestion exposure in acrylic acid leak accidents.

机构信息

Department of Nano & Biological Engineering, SeoKyeong University, Seoul, South Korea.

Department of Chemical & Biological Engineering, SeoKyeong University, Seoul, South Korea.

出版信息

Environ Sci Pollut Res Int. 2022 Apr;29(18):26648-26659. doi: 10.1007/s11356-021-17293-w. Epub 2021 Dec 2.

DOI:10.1007/s11356-021-17293-w
PMID:34854005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8989864/
Abstract

We established a hypothetical acrylic acid leak accident scenario, conducted a health risk assessment of local residents, and compared an actual accident case to the hypothetical scenario. The exposed subjects were divided into four age groups, and a noncarcinogenic health risk assessment was conducted for inhalation and soil ingestion. In the hypothetical scenario, 40 tons of acrylic acid was leaked in Ulsan for 1 h from midnight on January 1, 2017. In the actual accident case, 3 L of acrylic acid was leaked in Hwaseong, Gyeonggi Province, for 1 h from 11:00 am on March 5, 2020. The environmental concentration of acrylic acid was calculated using the dynamic multimedia environmental model. Noncarcinogenic assessment of the hypothetical scenario showed the hazard quotient exceeded 1 across all age groups, suggesting that a health risk is likely to occur due to inhalation exposure to acrylic acid resulting from a chemical accident. In addition, Hazard exceeded 1 until 2 h after the accident under the hypothetical scenario, indicating the likelihood of a health risk. Thus, we propose a methodology that can assess changing concentrations in a hazardous chemical leak from a chemical accident based on the time, place, the chemical's behaviors in different environmental media, and the health risk posed by the exposure of the chemical to local residents in the area affected by the accident.

摘要

我们建立了一个假设的丙烯酸泄漏事故场景,对当地居民进行了健康风险评估,并将实际事故案例与假设场景进行了比较。暴露的对象被分为四个年龄组,并对吸入和土壤摄入进行了非致癌健康风险评估。在假设场景中,2017 年 1 月 1 日午夜,有 40 吨丙烯酸在蔚山泄漏了 1 小时。在实际事故案例中,2020 年 3 月 5 日上午 11 点,在京畿道华城有 3 升丙烯酸泄漏了 1 小时。丙烯酸的环境浓度是使用动态多媒体环境模型计算的。假设场景下的非致癌评估显示,所有年龄组的危害系数都超过了 1,这表明由于化学事故导致的吸入丙烯酸而产生的健康风险很可能发生。此外,在假设场景下,事故发生后 2 小时内,危害超过 1,这表明存在健康风险。因此,我们提出了一种方法,可以根据时间、地点、化学物质在不同环境介质中的行为以及事故影响区域内当地居民接触化学物质所带来的健康风险,来评估化学事故中危险化学品泄漏的浓度变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/cfa18e1550d1/11356_2021_17293_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/e13a44a976ce/11356_2021_17293_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/590bb644899c/11356_2021_17293_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/05ee048485f1/11356_2021_17293_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/bb8950ea2afb/11356_2021_17293_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/0a7511bf342d/11356_2021_17293_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/4c4cbde3477e/11356_2021_17293_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/b795e46295d3/11356_2021_17293_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/cfa18e1550d1/11356_2021_17293_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/e13a44a976ce/11356_2021_17293_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/590bb644899c/11356_2021_17293_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/05ee048485f1/11356_2021_17293_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/bb8950ea2afb/11356_2021_17293_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/0a7511bf342d/11356_2021_17293_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/4c4cbde3477e/11356_2021_17293_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/b795e46295d3/11356_2021_17293_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbe/8989864/cfa18e1550d1/11356_2021_17293_Fig8_HTML.jpg

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