类风湿性血管炎患者血清中的血小板释放活性。

Platelet releasing activity in sera of patients with rheumatoid vasculitis.

作者信息

Cunningham T J, Medcalf R L, Mathews J D, Muirden K D

出版信息

Ann Rheum Dis. 1986 Jan;45(1):15-20. doi: 10.1136/ard.45.1.15.

DOI:10.1136/ard.45.1.15

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001808/

Abstract

Platelet releasing activity was found in sera fractionated by 30% ammonium sulphate in seven of 11 patients with systemic rheumatoid vasculitis, two of 16 patients with cutaneous rheumatoid vasculitis, and three of 18 patients with clinically uncomplicated rheumatoid arthritis. Serial studies in three patients suggest a key role of platelet activation by serum factors in the pathogenesis of systemic rheumatoid vasculitis. IgG rheumatoid factor or IgG containing immune complexes, or both, may be responsible for this platelet releasing activity.

摘要

在11例系统性类风湿性血管炎患者中的7例、16例皮肤类风湿性血管炎患者中的2例以及18例临床症状不复杂的类风湿性关节炎患者中的3例的血清中，发现经30%硫酸铵分级分离后的血清具有血小板释放活性。对3例患者的系列研究表明，血清因子激活血小板在系统性类风湿性血管炎的发病机制中起关键作用。IgG类风湿因子或含IgG的免疫复合物，或两者，可能是这种血小板释放活性的原因。

相似文献

1

Platelet releasing activity in sera of patients with rheumatoid vasculitis.类风湿性血管炎患者血清中的血小板释放活性。

Ann Rheum Dis. 1986 Jan;45(1):15-20. doi: 10.1136/ard.45.1.15.

2

Inhibition of C1q binding to antigen-antibody complexes by a factor in rheumatoid arthritis serum.类风湿关节炎血清中的一种因子对C1q与抗原-抗体复合物结合的抑制作用。

Rheumatol Int. 1986;6(5):205-8. doi: 10.1007/BF00541368.

3

Inhibition of C1q functions by RHP, a protein elevated in sera from patients with rheumatoid arthritis.类风湿关节炎患者血清中升高的一种蛋白质——RHP对C1q功能的抑制作用。

Complement. 1988;5(2):57-64. doi: 10.1159/000463036.

4

Platelet interactions with C1q in whole blood and in the presence of immune complexes or aggregated IgG.血小板在全血中以及在存在免疫复合物或聚集的IgG的情况下与C1q的相互作用。

Clin Immunol Immunopathol. 1992 Apr;63(1):45-50. doi: 10.1016/0090-1229(92)90092-3.

5

Detection and partial characterization of immune complexes in patients with rheumatoid arthritis plus Sjogren's syndrome and with Sjogren's syndrome alone.类风湿关节炎合并干燥综合征患者及单纯干燥综合征患者体内免疫复合物的检测与部分特性分析

Clin Exp Immunol. 1982 May;48(2):339-47.

6

Enhancement of Clq binding activity by IgM rheumatoid factor.IgM类风湿因子增强Clq结合活性。

J Rheumatol. 1985 Jun;12(3):444-8.

7

IgG and IgA antibodies to the collagen-like region of C1q in rheumatoid vasculitis.类风湿性血管炎中针对C1q胶原样区域的IgG和IgA抗体。

Arthritis Rheum. 1990 Nov;33(11):1646-54. doi: 10.1002/art.1780331107.

8

IgG rheumatoid factor, complement and immune complexes in rheumatoid synovitis and vasculitis: comparative and serial studies during cytotoxic therapy.类风湿性滑膜炎和血管炎中的IgG类风湿因子、补体及免疫复合物：细胞毒性治疗期间的比较研究和系列研究

Clin Exp Immunol. 1981 Jan;43(1):54-63.

9

Diminished uptake and degradation of soluble aggregates of IgG by monocytes of patients with rheumatoid arthritis and vasculitis.类风湿关节炎和血管炎患者单核细胞对IgG可溶性聚集体的摄取和降解减少。

J Rheumatol. 1987 Aug;14(4):680-5.

10

Histamine-triggered localized vasculitis in patients with seropositive rheumatoid arthritis.

J Am Acad Dermatol. 1983 Dec;9(6):845-51. doi: 10.1016/s0190-9622(83)70196-9.

引用本文的文献

1

Blood serotonin and joint pain in seropositive versus seronegative rheumatoid arthritis.血清阳性与血清阴性类风湿关节炎患者的血液血清素与关节疼痛

Mediators Inflamm. 2002 Aug;11(4):211-7. doi: 10.1080/09629350290000069.

2

Von Willebrand factor antigen in assessment of vasculitis in patients with connective tissue diseases.

Clin Rheumatol. 1994 Mar;13(1):34-8. doi: 10.1007/BF02229862.

本文引用的文献

1

The vascular lesions associated with rheumatoid arthritis.与类风湿关节炎相关的血管病变。

Bull Rheum Dis. 1959 Dec;10:201-2.

2

Platelet aggregation and release associated with immune complex formation in pig plasma.猪血浆中与免疫复合物形成相关的血小板聚集和释放。

J Lab Clin Med. 1980 Oct;96(4):654-65.

3

Platelet FcIgG receptor: increased expression in female platelets.血小板FcIgG受体：在女性血小板中表达增加。

Thromb Res. 1981;21(4-5):469-74. doi: 10.1016/0049-3848(81)90147-x.

4

IgG rheumatoid factor, complement and immune complexes in rheumatoid synovitis and vasculitis: comparative and serial studies during cytotoxic therapy.类风湿性滑膜炎和血管炎中的IgG类风湿因子、补体及免疫复合物：细胞毒性治疗期间的比较研究和系列研究

Clin Exp Immunol. 1981 Jan;43(1):54-63.

5

Platelet function in rheumatoid arthritis.类风湿关节炎中的血小板功能

Scand J Rheumatol. 1982;11(3):139-43. doi: 10.3109/03009748209098179.

6

IgG antiglobulins in rheumatoid arthritis and other arthritides: relationship with clinical features and other parameters.类风湿关节炎及其他关节炎中的IgG抗球蛋白：与临床特征及其他参数的关系

Ann Rheum Dis. 1981 Apr;40(2):127-31. doi: 10.1136/ard.40.2.127.

7

Serotonin content of platelets in inflammatory rheumatic diseases. Correlation with clinical activity.

Arthritis Rheum. 1983 Apr;26(4):532-40. doi: 10.1002/art.1780260413.

8

Responses of human arterial muscle to stable vasoactive substances released from human platelets by collagen and heat aggregated IgG.人体动脉平滑肌对胶原蛋白和热聚集免疫球蛋白G从人体血小板释放的稳定血管活性物质的反应。

Clin Exp Pharmacol Physiol. 1983 Sep-Oct;10(5):567-75. doi: 10.1111/j.1440-1681.1983.tb00225.x.

9

The effects of aggregated immunoglobulins on human blood platelets in relation to their complement-fixing abilities. I. Studies of immunoglobulins of different types.聚集免疫球蛋白对人血小板的影响及其补体结合能力。I. 不同类型免疫球蛋白的研究。

J Immunol. 1972 Sep;109(3):517-25.

10

The localization of circulating immune complexes in experimental serum sickness. The role of vasoactive amines and hydrodynamic forces.循环免疫复合物在实验性血清病中的定位。血管活性胺和流体动力的作用。

J Exp Med. 1968 Jan 1;127(1):119-36. doi: 10.1084/jem.127.1.119.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。