Department of Biochemical Research, Laboratory of Immunochemistry, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
Bull Exp Biol Med. 2021 Dec;172(2):218-222. doi: 10.1007/s10517-021-05366-2. Epub 2021 Dec 2.
We measured the level of natural antibodies (nAb) to glutamate and GABA reflecting the balance of excitation and inhibition systems and involved in the adaptation processes in athletes receiving normalized physical activity in the dynamics of training (figure skaters, football players, and people actively involved in sports). It was found that each subject has an individual immunological profile and its parameters change in accordance with the training load. The measured levels of nAbs to GABA and glutamate correlate the physical activity of a person. The surveyed football players were divided into 3 groups according to the results of the analysis. Subjects of the first group had reliably high immunological indices in comparison with the control and were at the peak of physical form; in the third group, low immunological indices relative to the control indicated exhaustion and fatigue. The indicators of the second group corresponded to normal and demonstrated the resource of adaptation to load. The developed method can be used for assessing person's readiness for physical activity.
我们测量了反映兴奋和抑制系统平衡的自然抗体（nAb）水平，这些自然抗体与接受正常体育活动的运动员的适应过程有关，包括花样滑冰运动员、足球运动员和积极参与体育运动的人。结果发现，每个人都有一个独特的免疫特征，其参数会随着训练负荷的变化而变化。测量到的 GABA 和谷氨酸的 nAb 水平与一个人的身体活动相关。根据分析结果，调查中的足球运动员被分为 3 组。与对照组相比，第一组的受试者具有可靠的高免疫学指标，处于身体状态的顶峰；第三组的免疫学指标相对对照组较低，表明已经筋疲力尽。第二组的指标与对照组相符，表明对负荷有适应资源。所开发的方法可用于评估人的身体活动准备情况。
