Guo Min, Liang Ying-Zhong, Cui Xiu-Ming, Shao Lin-Jiao, Li Yin-Fei, Yang Xiao-Yan
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Yunnan Provincial Key Laboratory of Panax Notoginseng, Kunming, China.
Nat Prod Res. 2023 May;37(9):1411-1415. doi: 10.1080/14786419.2021.2011271. Epub 2021 Dec 2.
A new chamigrane sesquiterpene, albocimea A (), and one known compound, 6-hydroxy-8-methoxy-3,5-dimethylisochroman (), were isolated from the rice fermentation of the fungus . The structure of new compound was elucidated by extensive spectroscopic analyses and electronic circular dichroism (ECD) calculations. Both compounds were evaluated for their cytotoxicity against five human cancer cell lines, but no significant cytotoxicity was found (IC values > 40 μM).
从真菌的大米发酵物中分离出一种新的菖蒲烷倍半萜，albocimea A（），以及一种已知化合物，6-羟基-8-甲氧基-3,5-二甲基异色满（）。通过广泛的光谱分析和电子圆二色性（ECD）计算阐明了新化合物的结构。对这两种化合物针对五种人类癌细胞系的细胞毒性进行了评估，但未发现明显的细胞毒性（IC值>40μM）。
