Nyström L, Rosén M, Wall S
Scand J Prim Health Care. 1986 Feb;4(1):5-12. doi: 10.3109/02813438609013963.
Why does a greater proportion of the population of northern Sweden suffer from such diseases as diabetes, stomach cancer and those of the circulatory system than people living in the southern part of the country? Are there any environmental factors that can explain these circumstances? It can be concluded from this study that the regional mortality pattern displayed here cannot be disregarded. The consistency of the finding is supported by the joint analysis of several data sources. The analyses in this study indicate that dietary habits, water hardness, and seasonal variations--rather than smoking habits or alcohol abuse--could be causal explanations for the regional mortality pattern in circulatory diseases. Diet and genetic factors may explain the regional variations in diabetes, while there is so far no evidence for associations between stomach cancer and any environmental factors. Thus, there is no correlation between stomach cancer and waterborne nitrate level in the 24 Swedish counties. This calls for further studies on the connections between stomach cancer and intake of salt, vitamins or trace elements. The preparation of foods could also have some impact on the incidence of stomach cancer.
为什么瑞典北部人口中患糖尿病、胃癌和循环系统疾病的比例比该国南部地区的人口更高？是否存在任何环境因素可以解释这些情况？从这项研究可以得出结论，这里所呈现的区域死亡率模式不容忽视。对多个数据源的联合分析支持了这一发现的一致性。本研究中的分析表明，饮食习惯、水的硬度和季节变化——而非吸烟习惯或酗酒——可能是循环系统疾病区域死亡率模式的因果解释。饮食和遗传因素可能解释糖尿病的区域差异，而目前尚无证据表明胃癌与任何环境因素之间存在关联。因此，在瑞典的24个县中，胃癌与水中硝酸盐水平之间没有相关性。这就需要进一步研究胃癌与盐、维生素或微量元素摄入之间的联系。食物的制备方式也可能对胃癌的发病率产生一定影响。
