Barsznica Yoan, Noiret Nicolas, Lambert Bérénice, Monnin Julie, De Pinho Claire, Hickel Julia, Masse Caroline, Richard-Devantoy Stephane, Morgny Cynthia, Bennabi Djamila, Haffen Emmanuel, Laurent Eric, Vandel Pierre, Chopard Gilles
Department of Clinical Psychiatry, Besançon University Hospital, Besançon, France.
Department of Neurology, Besançon University Hospital, Besançon, France.
Front Psychol. 2021 Nov 11;12:712347. doi: 10.3389/fpsyg.2021.712347. eCollection 2021.
Suicidal behaviors (SBs) are often associated with impaired performance on neuropsychological executive functioning (EF) measures that encourage the development of more specific and reliable tools. Recent evidence could suggest that saccadic movement using eye tracking can provide reliable information on EF in depressive elderly. The aim of this study was to describe oculomotor performances in elderly depressed patients with SB. To achieve this aim, we compared saccadic eye movement (SEM) performances in elderly depressed patients ( = 24) with SB and with no SB in prosaccade (PS) and antisaccade (AS) tasks under the gap, step, and overlap conditions. All participants also underwent a complete neuropsychological battery. Performances were impaired in patients with SB who exhibited less corrected AS errors and longer time to correct them than patients with no SB. Moreover, both groups had a similar performance for PS latencies and correct AS. These preliminary results suggested higher cognitive inflexibility in suicidal patients compared to non-suicidal. This inflexibility may explain the difficulty of the depressed elderly in generating solutions to the resurgence of suicidal ideation (SI) to respond adequately to stressful environments. The assessment of eye movement parameters in depressed elderly patients may be a first step in identifying high-risk patients for suicide.
自杀行为（SBs）通常与神经心理学执行功能（EF）测量中的表现受损相关，这促使人们开发更具体、可靠的工具。最近的证据表明，使用眼动追踪的扫视运动可以为抑郁老年人的执行功能提供可靠信息。本研究的目的是描述伴有自杀行为的老年抑郁症患者的眼动表现。为实现这一目标，我们比较了伴有自杀行为（n = 24）和不伴有自杀行为的老年抑郁症患者在间隙、阶梯和重叠条件下的前扫视（PS）和反扫视（AS）任务中的扫视眼动（SEM）表现。所有参与者还接受了完整的神经心理学测试。伴有自杀行为的患者表现受损，与不伴有自杀行为的患者相比，他们的反扫视错误校正较少，校正时间更长。此外，两组在前扫视潜伏期和正确反扫视方面表现相似。这些初步结果表明，与非自杀患者相比，自杀患者具有更高的认知灵活性。这种不灵活性可能解释了抑郁老年人在产生应对自杀意念（SI）复发的解决方案以充分应对压力环境方面的困难。评估老年抑郁症患者的眼动参数可能是识别自杀高危患者的第一步。
