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特发性脊柱侧凸的前后路融合手术:Lenke 5C型曲线患者健康相关生活质量与影像学结果的比较——来自瑞典脊柱注册中心的结果

Anterior posterior fusion surgery in idiopathic scoliosis: a comparison of health-related quality of life and radiographic outcomes in Lenke 5C curves - results from the Swedish spine registry.

作者信息

Charalampidis Anastasios, Möller Hans, Gerdhem Paul

机构信息

Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet.

Department of Reconstructive Orthopaedics, Karolinska University Hospital, Stockholm, Sweden.

出版信息

J Child Orthop. 2021 Oct 1;15(5):464-471. doi: 10.1302/1863-2548.15.210049.

Abstract

PURPOSE

To compare health-related quality of life and radiographic outcomes in patients treated with either anterior or posterior fusion surgery for Lenke 5C type idiopathic scoliosis.

METHODS

We used data from the Swedish spine registry and identified 59 patients with idiopathic scoliosis treated with fusion for Lenke 5C type curves; 27 patients underwent anterior surgery and 32 underwent posterior surgery. All patients had pre- and postoperative radiographic data and postoperative clinical data at a minimum of two years after surgery. Patient-reported outcomes measures included the Scoliosis Research Society (SRS)-22r, EuroQoL 5 dimensions 3 levels (EQ-5D-3L), EQ-visual analogue scale (VAS) and VAS for back pain. Radiographic assessment included measurement of the angle of the major curve, disc angulation below the lowest instrumented vertebra, curve flexibility, rate of curve correction, differences in sagittal parameters, number of fused vertebrae and length of fusion.

RESULTS

The mean age at surgery was 16 years in both groups. The mean follow-up time was 3.8 years. There were no significant differences in the SRS-22r score and EQ-5D-3L index at follow-up (all p ≥ 0.2). Postoperatively, both the anterior and posterior fusion group demonstrated a significant correction of the major curve (p ≤ 0.001) with no significant difference of the correction rate between the groups (p = 0.4). The posterior fusion group had shorter operative time (p < 0.001) and higher perioperative blood loss (p = 0.004) while the anterior group had lower number of fused vertebrae ( p< 0.001).

CONCLUSION

The type of surgical approach for Lenke 5C curves is not associated with differences in health-related quality of life, despite the lower number of fused vertebrae after anterior surgery.

LEVEL OF EVIDENCE

III.

摘要

目的

比较接受前路或后路融合手术治疗的Lenke 5C型特发性脊柱侧凸患者的健康相关生活质量和影像学结果。

方法

我们使用了瑞典脊柱登记处的数据,确定了59例接受Lenke 5C型曲线融合治疗的特发性脊柱侧凸患者;27例患者接受了前路手术,32例接受了后路手术。所有患者均有术前和术后的影像学数据以及术后至少两年的临床数据。患者报告的结局指标包括脊柱侧凸研究学会(SRS)-22r、欧洲五维健康量表3级(EQ-5D-3L)、EQ视觉模拟量表(VAS)和背痛VAS。影像学评估包括测量主弯角度、最低固定椎体下方的椎间盘成角、曲线柔韧性、曲线矫正率、矢状面参数差异、融合椎体数量和融合长度。

结果

两组患者的平均手术年龄均为16岁。平均随访时间为3.8年。随访时SRS-22r评分和EQ-5D-3L指数无显著差异(所有p≥0.2)。术后,前路和后路融合组的主弯均有显著矫正(p≤0.001),两组间矫正率无显著差异(p = 0.4)。后路融合组手术时间较短(p < 0.001),围手术期失血量较高(p = 0.004),而前路组融合椎体数量较少(p < 0.001)。

结论

尽管前路手术后融合椎体数量较少,但Lenke 5C曲线的手术方式与健康相关生活质量的差异无关。

证据级别

III级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6e/8582605/661018356635/jco-15-464-g0001.jpg

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