Sarwar Sobia, Rogers Sylvette, Mohamed Alaa S, Ogula Enitare, Ayantayo Rihanat A, Ahmed Ahmed, Shahzadi Iram, Kataria Saurabh, Singh Romil
Neurology, Independent Medical College, Faisalabad, PAK.
Family Medicine, Caribbean Medical University, Des Plaines, USA.
Cureus. 2021 Oct 25;13(10):e19036. doi: 10.7759/cureus.19036. eCollection 2021 Oct.
Coronavirus disease 19 (COVID-19) is caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). Apart from respiratory manifestations, COVID-19 can affect the nervous system due to its neurotropic features. Neurological manifestations and complications include headache, polyneuropathies, cerebrovascular accidents, seizures, encephalopathy, and demyelinating disease. We describe a case of multiple sclerosis, a demyelinating disease following COVID-19 infection, rarely reported in the literature. A 47-year-old female presented with fatigue, blurry vision, numbness, and signs of upper motor neuron lesions that had occurred three weeks after COVID-19 infection. Magnetic resonance imaging of the brain revealed demyelinating lesions in the periventricular area of both hemispheres, suggesting a demyelinating disease. A provisional diagnosis of multiple sclerosis was made. Her condition improved after the commencement of methylprednisolone.
新型冠状病毒肺炎（COVID-19）由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起。除呼吸系统表现外，COVID-19因其嗜神经特性可影响神经系统。神经学表现和并发症包括头痛、多发性神经病、脑血管意外、癫痫发作、脑病和脱髓鞘疾病。我们描述了一例新型冠状病毒感染后发生的脱髓鞘疾病——多发性硬化症病例，该病例在文献中鲜有报道。一名47岁女性在感染COVID-19三周后出现疲劳、视力模糊、麻木以及上运动神经元损伤体征。脑部磁共振成像显示双侧脑室周围区域有脱髓鞘病变，提示为脱髓鞘疾病。初步诊断为多发性硬化症。开始使用甲泼尼龙治疗后，她的病情有所改善。
