Neurology Department, Complejo Hospitalario Universitario de Albacete, Castilla- La Mancha, Spain.
Neurology Department, Complejo Hospitalario Universitario de Albacete, Castilla- La Mancha, Spain.
Mult Scler Relat Disord. 2020 Oct;45:102377. doi: 10.1016/j.msard.2020.102377. Epub 2020 Jul 7.
SARS-CoV-2 infection can produce neurological features. The most common are headache, anosmia and dysgeusia but patients may also develop other central nervous system (CNS) injuries. We present a patient affected by Covid-19 who initially consulted for decreased visual acuity. The MRI showed inflammation in the right optic nerve and demyelinating lesions in the CNS. We speculate that an immune mechanism induced by SARS-CoV-2, which can activate lymphocytes and an inflammatory response, plays a role in the clinical onset of the disease. This pathogen may be associated with either the triggering or the exacerbation of inflammatory/demyelinating disease.
SARS-CoV-2 感染可产生神经系统表现。最常见的是头痛、嗅觉缺失和味觉障碍，但患者也可能出现其他中枢神经系统（CNS）损伤。我们报告了 1 例 COVID-19 患者，其最初就诊的原因是视力下降。MRI 显示右侧视神经炎症和 CNS 脱髓鞘病变。我们推测，由 SARS-CoV-2 引发的免疫机制在疾病的临床发病中起作用，该机制可激活淋巴细胞和炎症反应。该病原体可能与炎症/脱髓鞘疾病的触发或恶化有关。
