State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Dept. of Oral Medicine, Stomatology Center, Shenzhen People,s Hospital, Shenzhen 518020, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Dec 1;39(6):724-727. doi: 10.7518/hxkq.2021.06.016.
Drug-induced pemphigus (DIP) is a special type of pemphigus, and its pathogenesis, characteristics of treatment, and prognosis are closely related to the inducing drugs. This article reports the diagnosis and treatment of DIP (pemphigus vulgaris) caused by the administration of rifampin to a patient with tuberculosis. Combined with the literature, we discussed the types, pathogenesis, differential diagnosis, and treatment principles of DIP. We propose that in the oral clinical practice for patients with pemphigus vulgaris, the importance of investigating suspected drugs that induce DIP should be emphasized.
药物诱导性天疱疮（DIP）是天疱疮的特殊类型，其发病机制、治疗特点和预后与诱导药物密切相关。本文报道了一例由利福平治疗肺结核引起的 DIP（寻常型天疱疮）的诊断和治疗。结合文献，我们讨论了 DIP 的类型、发病机制、鉴别诊断和治疗原则。我们提出，在口腔临床实践中，对于寻常型天疱疮患者，应强调调查可疑诱导 DIP 药物的重要性。
