Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna.
Clinic for Pediatric and Preventive Dentistry, School of Dental Dedicine, University of Belgrade, Belgrade, Serbia.
J Esthet Restor Dent. 2022 Jan;34(1):55-64. doi: 10.1111/jerd.12841. Epub 2021 Dec 3.
This study comprehensively reviewed clinical trials that investigated the effect of immediate dentin sealing (IDS) technique on postoperative sensitivity (POS) and clinical performance of indirect restorations.
The systematic review was conducted according to the preferred reporting items for systematic reviews and meta-analyses statement, and was guided by the PICOS strategy. Clinical trials in which adult patients received at least one indirect restoration cemented with IDS approach and one restoration cemented following the delayed dentin sealing (DDS) were considered.
Following title screening and full-text reading, four studies met the inclusion criteria and were included for qualitative synthesis, while two studies were selected for quantitative synthesis. According to Risk of bias-2 tool, two studies were classified as "some concerns" for the outcome POS. No statistically significant differences were found between teeth restored with indirect restorations using the IDS and DDS approach for POS (p > 0.05), neither at the baseline (very low certainty of evidence according to GRADE) nor after 2 years of follow-up (low certainty of evidence according to GRADE).
There is low-certainty evidence that IDS does not reduce POS in teeth restored with indirect restorations.
There is no clinical evidence to favor IDS over DDS when restoring teeth with indirect restorations.
本研究全面综述了评价即刻牙本质封闭（IDS）技术对术后敏感（POS）和间接修复体临床性能影响的临床试验。
系统评价遵循系统评价和荟萃分析报告的首选项目声明，并遵循 PICOS 策略。纳入至少接受过 IDS 间接修复体粘固和 DDS 延迟牙本质封闭（DDS）后粘固间接修复体的成年患者的临床试验。
经标题筛选和全文阅读，4 项研究符合纳入标准，进行定性综合分析，2 项研究进行定量综合分析。根据风险偏倚-2 工具，有 2 项研究对 POS 结果的评估存在“一些担忧”。使用 IDS 和 DDS 方法修复的间接修复体的牙齿在 POS 方面没有统计学差异（p>0.05），基线时无差异（根据 GRADE 为极低确定性证据），2 年后随访时也无差异（根据 GRADE 为低确定性证据）。
有低确定性证据表明，IDS 并不能降低间接修复体修复的牙齿的 POS。
在间接修复体修复牙齿时，没有临床证据支持 IDS 优于 DDS。
