Department of Nosocomial Infection Management, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Wuchang District Center for Disease Control and Prevention, Wuhan, Hubei, China.
AIDS Res Ther. 2021 Dec 4;18(1):92. doi: 10.1186/s12981-021-00416-1.
This study aims to evaluate the safety of inactivated COVID-19 vaccine among adult people living with HIV (PLWH). In total, 259 PLWH who received at least one dose of inactivated COVID-19 vaccine were enrolled, and post-vaccination adverse events (AEs) were evaluated seven days following each vaccination dose. The overall AE frequency was 22.8% after dose one, which was higher than after dose two (10.2%) (P < 0.001). No severe side event or vaccine safety concern was observed. Our finding was essential in reducing vaccine hesitancy among PLWH.
本研究旨在评估在成人 HIV 感染者（PLWH）中使用灭活 COVID-19 疫苗的安全性。共纳入 259 名至少接种过一剂灭活 COVID-19 疫苗的 PLWH，在每次接种后 7 天评估接种后不良事件（AE）。第 1 剂后的总体 AE 发生率为 22.8%，高于第 2 剂（10.2%）（P<0.001）。未观察到严重的不良反应或疫苗安全性问题。我们的发现对于减少 PLWH 中的疫苗犹豫至关重要。
