Department of Anaesthesiology and IntensiveTherapy, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.
The Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
J Alzheimers Dis. 2022;85(2):519-525. doi: 10.3233/JAD-210304.
Using group-aggregated results and snapshot assessments of cognitive performance may prove problematic if the assessed construct shows substantial and rapid variation over time. To illustrate the significance of this issue, we analyzed cognitive performance data of ten older adults undergoing daily computerized cognitive assessments (CogState Brief Battery) for 36-93 days. In all cases, the day-to-day intra-individual variability was substantial when compared with group-level, between-person variability. This indicates that the results of studies using single snapshot assessments of cognitive functioning should be interpreted with caution. Additionally, group-aggregated measures of cognitive performance may not directly extrapolate to an individual.
如果所评估的结构在时间上表现出显著且快速的变化，那么使用群体聚合结果和认知表现的快照评估可能会出现问题。为了说明这个问题的重要性，我们分析了 10 名老年人的认知表现数据，这些老年人接受了 36-93 天的日常计算机认知评估（CogState 简短电池）。在所有情况下，与个体间的群体水平变异性相比，个体内的日间变异性都很大。这表明，使用单次快照评估认知功能的研究结果应谨慎解释。此外，认知表现的群体聚合度量值可能无法直接外推到个体。
