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梅尼埃病:新指南、亚型、影像学等。

Ménière's disease: new guidelines, subtypes, imaging, and more.

机构信息

Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA.

出版信息

Curr Opin Neurol. 2022 Feb 1;35(1):90-97. doi: 10.1097/WCO.0000000000001021.

Abstract

PURPOSE OF REVIEW

This article reviews recent developments in Ménière's disease including etiologic, diagnostic, and therapeutic investigations that have changed the landscape for medical providers. These updates shed light onto the complex nature of Ménière's disease and generate additional means to provide optimal care to patients.

RECENT FINDINGS

Given the multifactorial cause of Ménière's disease, five subtypes of Ménière's disease have recently been proposed. A knowledge of these subtypes will aid in the development of an appropriate treatment algorithm. Although newer treatments have not been developed, stepwise treatment algorithms have been proposed and can improve patient care. New MRI modalities and serum testing hold promise as clinical clues and biomarkers.

SUMMARY

As these updated diagnostic criteria are used, Ménière's disease can be identified and treated more precisely. This will in turn allow for future randomized controlled studies to improve the quality of treatment options available. Future imaging, vestibular testing, and the potential for serum biomarkers may illuminate additional diagnostic criteria, only furthering the improvement in clinical care.

摘要

目的综述

本文综述了梅尼埃病的最新研究进展,包括病因学、诊断和治疗方面的研究,这些研究改变了医疗服务提供者的治疗模式。这些更新揭示了梅尼埃病的复杂性,并为患者提供最佳护理提供了更多的方法。

最近的发现

鉴于梅尼埃病的多因素病因,最近提出了五种梅尼埃病亚型。了解这些亚型将有助于制定适当的治疗方案。尽管尚未开发出新的治疗方法,但已经提出了逐步治疗方案,可以改善患者的护理。新的 MRI 模式和血清检测有望成为临床线索和生物标志物。

总结

随着这些更新的诊断标准的应用,梅尼埃病可以得到更精确的诊断和治疗。这反过来又将允许未来进行随机对照研究,以提高现有治疗选择的质量。未来的影像学、前庭测试以及血清生物标志物的潜力可能会揭示更多的诊断标准,进一步提高临床护理水平。

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