Department of Infectious Diseases, Nagoya University Hospital, Japan.
Department of Infectious Diseases, Nagoya University Hospital, Japan.
J Infect Chemother. 2022 Feb;28(2):315-318. doi: 10.1016/j.jiac.2021.10.030. Epub 2021 Dec 2.
A 93-year-old woman was diagnosed with Lysinibacillus fusiformis bacteremia complicated with coma blisters. Initial gram staining for L. fusiformis indicated the presence of gram-negative rods; however, subsequent staining of colonies from Mueller-Hinton agar revealed the presence of gram-positive and gram-negative rods with spherical endospores, and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (VITEK ® MS and microflex® LT/SH) definitively identified the organism as L. fusiformis. The two-week administration of piperacillin/tazobactam and ampicillin resulted in an improvement of the patient's general condition, and the skin lesions gradually improved.
一位 93 岁女性被诊断为梭菌属伴昏迷水疱的 Fusobacterium 菌血症。最初对梭菌属的革兰氏染色显示存在革兰氏阴性杆菌;然而,随后对 Mueller-Hinton 琼脂上的菌落进行染色显示存在革兰氏阳性和革兰氏阴性杆菌,具有球形内生孢子,基质辅助激光解吸/电离飞行时间质谱(VITEK ® MS 和 microflex® LT/SH)明确鉴定该生物体为梭菌属。哌拉西林/他唑巴坦和氨苄西林的两周治疗使患者的一般状况得到改善,皮肤损伤逐渐改善。