肝脏微粒体组分对肌醇三磷酸的结合
Binding of inositol trisphosphate by a liver microsomal fraction.
作者信息
Spät A, Fabiato A, Rubin R P
出版信息
Biochem J. 1986 Feb 1;233(3):929-32. doi: 10.1042/bj2330929.
Abstract
Accumulating evidence suggests that the increase in cytosolic Ca2+ induced by receptor agonists is mediated by inositol 1,4,5-trisphosphate, a product of phospholipase C-mediated breakdown of phosphatidylinositol 4,5-bisphosphate. The present study employs inositol tris[32P]phosphate to demonstrate a specific receptor binding site in a microsomal fraction of rat liver.
摘要
越来越多的证据表明，受体激动剂诱导的胞质Ca2+增加是由肌醇1,4,5-三磷酸介导的，肌醇1,4,5-三磷酸是磷脂酶C介导的磷脂酰肌醇4,5-二磷酸分解产物。本研究使用肌醇三[32P]磷酸来证明大鼠肝脏微粒体部分存在特异性受体结合位点。
相似文献
1
Binding of inositol trisphosphate by a liver microsomal fraction.
Biochem J. 1986 Feb 1;233(3):929-32. doi: 10.1042/bj2330929.
2
Pathway for inositol 1,3,4-trisphosphate and 1,4-bisphosphate metabolism.
Proc Natl Acad Sci U S A. 1987 Apr;84(8):2170-4. doi: 10.1073/pnas.84.8.2170.
3
Kinetic analysis of A23187-mediated polyphosphoinositide breakdown in rat cortical synaptosomes suggests that inositol bisphosphate does not arise primarily by degradation of inositol trisphosphate.
J Neurochem. 1989 Aug;53(2):399-407. doi: 10.1111/j.1471-4159.1989.tb07348.x.
4
Binding of inositol phosphates and induction of Ca2+ release from pituitary microsomal fractions.
Biochem J. 1987 Jun 1;244(2):493-6. doi: 10.1042/bj2440493.
5
Inositol (1,4,5)trisphosphate-promoted Ca2+ release from microsomal fractions of rat liver.
Biochem Biophys Res Commun. 1984 May 16;120(3):858-64. doi: 10.1016/s0006-291x(84)80186-2.
6
Inositol 1,3,4,5-tetrakisphosphate and not phosphatidylinositol 3,4-bisphosphate is the probable precursor of inositol 1,3,4-trisphosphate in agonist-stimulated parotid gland.
Biochem J. 1986 Sep 1;238(2):501-6. doi: 10.1042/bj2380501.
7
Gonadotropin-releasing hormone (GnRH) rapidly stimulates the formation of inositol phosphates and diacyglycerol in rat granulosa cells: further evidence for the involvement of Ca2+ and protein kinase C in the action of GnRH.
Endocrinology. 1986 Jun;118(6):2561-71. doi: 10.1210/endo-118-6-2561.
8
Secretagogue-induced formation of inositol phosphates in rat exocrine pancreas. Implications for a messenger role for inositol trisphosphate.
Biochem J. 1984 Apr 15;219(2):655-9. doi: 10.1042/bj2190655.
9
Metabolism of inositol phosphates in parotid cells: implications for the pathway of the phosphoinositide effect and for the possible messenger role of inositol trisphosphate.
Life Sci. 1984 Apr 2;34(14):1347-55. doi: 10.1016/0024-3205(84)90006-7.
10
Quantitative changes in inositol 1,4,5-trisphosphate in chemoattractant-stimulated neutrophils.
J Biol Chem. 1986 Nov 25;261(33):15644-7.
引用本文的文献
1
Signaling Interactions in the Adrenal Cortex.
Front Endocrinol (Lausanne). 2016 Feb 29;7:17. doi: 10.3389/fendo.2016.00017. eCollection 2016.
2
Special features of mitochondrial Ca²⁺ signalling in adrenal glomerulosa cells.
Pflugers Arch. 2012 Jul;464(1):43-50. doi: 10.1007/s00424-012-1086-y. Epub 2012 Mar 7.
3
Binding of inositol phosphates and induction of Ca2+ release from pituitary microsomal fractions.
Biochem J. 1987 Jun 1;244(2):493-6. doi: 10.1042/bj2440493.
4
5
Stereospecific mobilization of intracellular Ca2+ by inositol 1,4,5-triphosphate. Comparison with inositol 1,4,5-trisphosphorothioate and inositol 1,3,4-trisphosphate.
Biochem J. 1988 Aug 1;253(3):901-5. doi: 10.1042/bj2530901.
6
Effects of hypoxia on contractile responses of rabbit aortic strips to transmural electrical stimulation.
Naunyn Schmiedebergs Arch Pharmacol. 1988 Sep;338(3):275-81. doi: 10.1007/BF00173400.
7
Properties of intracellular calcium stores in pregnant rat myometrium.
Br J Pharmacol. 1988 Sep;95(1):284-90. doi: 10.1111/j.1476-5381.1988.tb16575.x.
8
Angiotensin-stimulated production of inositol trisphosphate isomers and rapid metabolism through inositol 4-monophosphate in adrenal glomerulosa cells.
Proc Natl Acad Sci U S A. 1986 Dec;83(24):9323-7. doi: 10.1073/pnas.83.24.9323.
9
Characterization of a membrane protein from brain mediating the inhibition of inositol 1,4,5-trisphosphate receptor binding by calcium.
Biochem J. 1988 Sep 15;254(3):701-5. doi: 10.1042/bj2540701.
10
Cyclic AMP-dependent phosphorylation of a brain inositol trisphosphate receptor decreases its release of calcium.
Proc Natl Acad Sci U S A. 1988 Nov;85(22):8747-50. doi: 10.1073/pnas.85.22.8747.
本文引用的文献
1
[Paper chromatography of inositol phosphates; use in study of hydrolytic degradation of inositol hexaphosphate].
Bull Soc Chim Biol (Paris). 1956 Sep 4;38(5-6):871-83.
2
Calcium pools in saponin-permeabilized guinea pig hepatocytes.
J Biol Chem. 1983 Dec 25;258(24):15336-45.
3
Inositol (1,4,5)trisphosphate-promoted Ca2+ release from microsomal fractions of rat liver.
Biochem Biophys Res Commun. 1984 May 16;120(3):858-64. doi: 10.1016/s0006-291x(84)80186-2.
4
myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.
J Biol Chem. 1984 Mar 10;259(5):3077-81.
5
Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes.
Biochem J. 1984 Dec 15;224(3):741-6. doi: 10.1042/bj2240741.
6
Effect of inositol-1,4,5-trisphosphate on isolated subcellular fractions of rat pancreas.
J Membr Biol. 1984;81(3):241-53. doi: 10.1007/BF01868717.
7
Inositol trisphosphates in carbachol-stimulated rat parotid glands.
Biochem J. 1984 Oct 1;223(1):237-43. doi: 10.1042/bj2230237.
8
Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate.
Nature. 1984;309(5968):562-4. doi: 10.1038/309562a0.
9
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol.
Biochem J. 1983 Jun 15;212(3):849-58. doi: 10.1042/bj2120849.
10
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.
Biochem J. 1983 May 15;212(2):473-82. doi: 10.1042/bj2120473.
Zotero 插件