Ning Songyi, Lu Xiang, Zhao Min, Wang Xiaochun, Yang Shixing, Shen Quan, Wang Hao, Zhang Wen
School of Medicine, Jiangsu University, Zhenjiang, China.
Department of Clinical Laboratory, The Affiliated Huai'an Hospital of Xuzhou Medical University, Xuzhou, China.
Front Vet Sci. 2021 Nov 12;8:767494. doi: 10.3389/fvets.2021.767494. eCollection 2021.
The giant panda () is one of the most endangered mammals in the world; anthropogenic habitat loss and poaching still threaten the survival of wild pandas. Viral infection has become one of the potential threats to the health of these animals, but the available information related to these infections is still limited. In order to detect possible vertebrate viruses, the virome in the fecal samples of seven wild giant pandas from Qinling Mountains was investigated by using the method of viral metagenomics. From the fecal virome of wild giant pandas, we determined six nearly complete genomes belonging to the order , two of which may be qualified as a novel virus family or genus. In addition, four complete genomes belonging to the family were also fully characterized. This virological investigation has increased our understanding of the gut viral community in giant pandas. Whether these viruses detected in fecal samples can really infect giant panda needs further research.
大熊猫（ ）是世界上最濒危的哺乳动物之一；人为造成的栖息地丧失和偷猎仍然威胁着野生大熊猫的生存。病毒感染已成为这些动物健康的潜在威胁之一，但与这些感染相关的现有信息仍然有限。为了检测可能的脊椎动物病毒，采用病毒宏基因组学方法对来自秦岭的7只野生大熊猫粪便样本中的病毒群落进行了调查。从野生大熊猫的粪便病毒群落中，我们确定了6个属于 目的近乎完整的基因组，其中两个可能有资格成为新的病毒科或属。此外，还对4个属于 科的完整基因组进行了全面表征。这项病毒学调查增进了我们对大熊猫肠道病毒群落的了解。粪便样本中检测到的这些病毒是否真的能感染大熊猫还需要进一步研究。
