Walsh Nicholas, Carney Patrick C, Streu Shayna, Thompson Margret, Johnson Philippa J
Cornell University College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.
University of Missouri College of Veterinary Medicine, Columbia, MO, United States.
Front Vet Sci. 2021 Nov 16;8:768709. doi: 10.3389/fvets.2021.768709. eCollection 2021.
Since magnetic resonance imaging (MRI) was introduced, it has become increasingly available and technologically improved. Studies have documented the prevalence of specific pathologies, however no previous veterinary studies have investigated the prevalence and distribution of pathology across all MRIs performed at a single institution. The present study aimed to evaluate the prevalence of MRI-diagnosed brain lesions and correlate these to patient signalment and presenting complaint. Archived MRI brain scans from 805 dogs were reviewed retrospectively. One board-certified veterinary radiologist at the institution retrospectively evaluated all reports to determine the most clinically pertinent imaging diagnosis for each case. Breed, age, and presenting complaint were obtained from the medical record for each patient. The most common imaging diagnoses across all dogs reviewed were no significant findings (35.16%), asymmetric encephalopathy or meningoencephalopathy (19.75%), and extra-axial intracranial mass (11.18%). Age of dogs differed by diagnosis ( <0.0001), with the median age of dogs diagnosed with a brain mass being greater than that of dogs with no significant findings and dogs with asymmetric encephalopathy or meningoencephalopathy (both <0.0083). In dogs presenting with seizures, the odds of a brain mass increased with each additional year of age [ <0.0001, odds ratio 1.26 (95% CI 1.16-1.37)], whereas the odds of no significant finding [ <0.0001, OR 0.87 (0.82-0.93)] decreased. Our findings provide overview information on the types of disease observed in the clinical population and allow us to detect correlations between imaging diagnoses, presenting complaints, and signalment.
自从磁共振成像（MRI）被引入以来，其可用性日益提高，技术也不断改进。已有研究记录了特定病理情况的患病率，然而此前尚无兽医研究调查过在单一机构进行的所有MRI检查中病理情况的患病率及分布。本研究旨在评估MRI诊断的脑损伤患病率，并将其与患畜的信号转导和就诊主诉相关联。对805只犬的存档MRI脑部扫描进行了回顾性分析。该机构的一名获得委员会认证的兽医放射科医生对所有报告进行了回顾性评估，以确定每个病例最具临床相关性的影像诊断。从每只患畜的病历中获取品种、年龄和就诊主诉信息。在所有接受检查的犬中，最常见的影像诊断为无显著异常（35.16%）、不对称性脑病或脑膜脑脊髓炎（19.75%）以及轴外颅内肿块（11.18%）。不同诊断的犬年龄存在差异（<0.0001），被诊断为脑肿瘤的犬的中位年龄高于无显著异常的犬以及患有不对称性脑病或脑膜脑脊髓炎的犬（均<0.0083）。在以癫痫发作就诊的犬中，每增加一岁，患脑肿瘤的几率就会增加[<0.0001，优势比为1.26（95%可信区间1.16 - 1.37）]，而无显著异常的几率[<0.0001，优势比为0.87（0.82 - 0.93）]则会降低。我们的研究结果提供了关于临床群体中观察到的疾病类型的概述信息，并使我们能够检测影像诊断、就诊主诉和信号转导之间的相关性。
