ABO血型对新冠病毒肺炎患者住院时间的影响（按年龄划分）
Effect of ABO blood groups on length of hospital stay according to age in Covid-19 patients.
作者信息
Gursoy Vildan, Avci Suna
机构信息
Usak Education and Training Hospital, University of Usak, Usak, Turkey.
Bursa Yuksek Ihtisas Education and Training Hospital, University of Health Sciences, Bursa, Turkey.
出版信息
Hematol Transfus Cell Ther. 2022 Jan-Mar;44(1):7-12. doi: 10.1016/j.htct.2021.08.013. Epub 2021 Nov 29.
INTRODUCTION
Coronavirus Disease 2019 (COVID-19) is a novel viral disease with person-to-person transmission that has spread to many countries since the end of 2019. Although many unknowns were resolved within a year and the vaccine is available, it is still a major global health problem.
OBJECTIVE
COVID-19 infection may present with a considerably wide spectrum of severity and host factors play a significant role in determining the course of the disease. One of these factors is blood groups. Based on previous experience, it is believed that the ABO blood group type affects prognosis, treatment response and length of stay in the hospital. In this study, our aim was to evaluate whether the blood group had an effect on the length of the hospital stay. To the best of our knowledge, no previous studies have assessed the effect of ABO blood groups, as well as age, on the length of the hospital stay in these settings.
METHODS
In this retrospective cohort study, 969 patients admitted to our hospital between March 15, 2020 and May 15, 2020 were evaluated. The patients were divided into 4 groups according to ABO blood groups. The effect of the ABO blood group by age on the course of the disease, need for intensive care, duration of hospitalization and mortality in patients with COVID-19 infection, especially in geriatric patients, was evaluated.
RESULTS
Of all the patients, 9.1% required admission to the intensive care unit (ICU), of whom 83% died. The average length of ICU stay was 11 days (0 - 59). The observed mortality rates in blood groups A, B, AB and 0 were 86.4%, 93.3%, 80.0% and 70.8%, respectively, indicating similar death rates in all ABO blood types. When the Rh phenotype was taken into consideration, no significant changes in results were seen.
CONCLUSION
As a result, we could not observe a significant relationship between blood groups and clinical outcomes in this study, which included a sample of Turkish patients with COVID-19.
引言
2019年冠状病毒病（COVID-19）是一种具有人传人特性的新型病毒性疾病，自2019年底以来已传播至许多国家。尽管在一年内解决了许多未知问题且已有疫苗可用，但它仍然是一个重大的全球健康问题。
目的
COVID-19感染的严重程度可能有很大差异，宿主因素在决定疾病进程中起着重要作用。其中一个因素是血型。根据以往经验，认为ABO血型类型会影响预后、治疗反应和住院时间。在本研究中，我们的目的是评估血型是否对住院时间有影响。据我们所知，此前尚无研究评估ABO血型以及年龄对这些情况下住院时间的影响。
方法
在这项回顾性队列研究中，对2020年3月15日至2020年5月15日期间我院收治的969例患者进行了评估。患者根据ABO血型分为4组。评估了ABO血型按年龄对COVID-19感染患者，尤其是老年患者的疾病进程、重症监护需求、住院时间和死亡率的影响。
结果
所有患者中，9.1%需要入住重症监护病房（ICU），其中83%死亡。ICU平均住院时间为11天（0 - 59天）。A、B、AB和O血型的观察到的死亡率分别为86.4%、93.3%、80.0%和70.8%，表明所有ABO血型的死亡率相似。考虑Rh表型时，结果未见显著变化。
结论
因此，在这项纳入了土耳其COVID-19患者样本的研究中，我们未观察到血型与临床结局之间存在显著关系。
Zotero 插件