• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

接受托珠单抗治疗的COVID-19患者出现金黄色葡萄球菌性肋软骨炎和胸壁脓肿。

<em>Staphylococcus aureus costochondritis</em> and chest wall abscess in a COVID-19 patient treated with tocilizumab.

作者信息

Ergenç İlkay, Şanal Toprak Canan, Odabaşı Zekaver

机构信息

Department of Gastroenterology, Marmara University School of Medicine, Istanbul, Turkey.

Department of Physical Medicine and Rehabilitation, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Turk J Phys Med Rehabil. 2021 Sep 1;67(3):382-385. doi: 10.5606/tftrd.2021.8208. eCollection 2021 Sep.

DOI:10.5606/tftrd.2021.8208
PMID:34870129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8607000/
Abstract

Coronavirus disease 2019 (COVID-19) is a worldwide pandemic, causing a global health threat. Up to 15% of the confirmed cases develop severe disease, requiring hospitalization or intensive care unit (ICU) admission. Tocilizumab, an IL-6 receptor antagonist, is a promising treatment of severe pneumonia with acute respiratory distress syndrome (ARDS) or cytokine release syndrome (CRS) in the course of COVID-19. We report a suppurative costochondritis and chest wall abscess in a severe COVID-19 patient treated with tocilizumab.

摘要

2019冠状病毒病(COVID-19)是一场全球大流行疾病,对全球健康构成威胁。高达15%的确诊病例会发展为重症疾病,需要住院治疗或入住重症监护病房(ICU)。托珠单抗是一种白细胞介素-6受体拮抗剂,是治疗COVID-19过程中出现的伴有急性呼吸窘迫综合征(ARDS)或细胞因子释放综合征(CRS)的重症肺炎的一种有前景的治疗方法。我们报告了一例在接受托珠单抗治疗的重症COVID-19患者中发生的化脓性肋软骨炎和胸壁脓肿。

相似文献

1
<em>Staphylococcus aureus costochondritis</em> and chest wall abscess in a COVID-19 patient treated with tocilizumab.接受托珠单抗治疗的COVID-19患者出现金黄色葡萄球菌性肋软骨炎和胸壁脓肿。
Turk J Phys Med Rehabil. 2021 Sep 1;67(3):382-385. doi: 10.5606/tftrd.2021.8208. eCollection 2021 Sep.
2
Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019: Survival and Clinical Outcomes.托珠单抗治疗 COVID-19 住院患者细胞因子释放综合征:生存和临床结局。
Chest. 2020 Oct;158(4):1397-1408. doi: 10.1016/j.chest.2020.06.006. Epub 2020 Jun 15.
3
Tocilizumab as a Treatment for 'Cytokine Storm Syndrome' in COVID-19: A Case Report.托珠单抗治疗 COVID-19 中的“细胞因子风暴综合征”:一例报告。
Acta Med Indones. 2021 Apr;53(2):194-201.
4
Tocilizumab in SARS-CoV-2 Patients with the Syndrome of Cytokine Storm: A Narrative Review.托珠单抗治疗细胞因子风暴综合征的 SARS-CoV-2 患者:一项叙述性综述。
Rev Recent Clin Trials. 2021;16(2):138-145. doi: 10.2174/1574887115666200917110954.
5
Primary chest wall abscess caused by Escherichia coli costochondritis.大肠杆菌肋软骨炎致原发性胸壁脓肿。
Am J Med Sci. 2011 Sep;342(3):241-6. doi: 10.1097/MAJ.0b013e31821bc1b0.
6
Recovery of COVID-19 acute respiratory distress syndrome with tocilizumab: successful outcome in two critically ill patients.托珠单抗治疗 COVID-19 急性呼吸窘迫综合征:两例危重症患者的成功转归。
Immunotherapy. 2020 Oct;12(15):1127-1132. doi: 10.2217/imt-2020-0154. Epub 2020 Jul 14.
7
Early Use of Tocilizumab May Prevent Clinical Deterioration in Select COVID-19 Patients: A Case Series.托珠单抗的早期使用可能预防部分新冠患者的临床病情恶化:病例系列研究
Cureus. 2020 Jul 14;12(7):e9187. doi: 10.7759/cureus.9187.
8
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome.白细胞介素-6 转导信号诱导细胞因子释放综合征中的血管内皮细胞产生纤溶酶原激活物抑制剂-1。
Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22351-22356. doi: 10.1073/pnas.2010229117. Epub 2020 Aug 21.
9
Effectiveness of Tocilizumab in a COVID-19 Patient with Cytokine Release Syndrome.托珠单抗在一名细胞因子释放综合征的COVID-19患者中的疗效
Eur J Case Rep Intern Med. 2020 May 22;7(6):001731. doi: 10.12890/2020_001731. eCollection 2020.
10
Rapid and Impressive Response to a Combined Treatment with Single-Dose Tocilizumab and NIV in a Patient with COVID-19 Pneumonia/ARDS.COVID-19 肺炎/ARDS 患者采用托珠单抗单剂量联合 NIV 治疗取得快速显著疗效。
Medicina (Kaunas). 2020 Jul 27;56(8):377. doi: 10.3390/medicina56080377.

引用本文的文献

1
Two Cases of Lung Abscess and Pleuritis in Severe COVID-19 Patients.重症新型冠状病毒肺炎患者并发肺脓肿和胸膜炎2例
Cureus. 2024 Jun 3;16(6):e61614. doi: 10.7759/cureus.61614. eCollection 2024 Jun.
2
Tietze's Syndrome Post-COVID-19 Infection in an Adult Patient.一名成年患者新冠病毒感染后的蒂策综合征
Cureus. 2022 Jul 31;14(7):e27499. doi: 10.7759/cureus.27499. eCollection 2022 Jul.
3
COVID-19 musculoskeletal involvement in children.儿童新冠病毒感染相关的肌肉骨骼表现

本文引用的文献

1
Consideration of Severe Coronavirus Disease 2019 As Viral Sepsis and Potential Use of Immune Checkpoint Inhibitors.将重症2019冠状病毒病视为病毒性脓毒症及免疫检查点抑制剂的潜在应用
Crit Care Explor. 2020 Jun 11;2(6):e0141. doi: 10.1097/CCE.0000000000000141. eCollection 2020 Jun.
2
Tocilizumab not associated with increased infection risk after CAR T-cell therapy: implications for COVID-19?托珠单抗与CAR T细胞治疗后感染风险增加无关:对COVID-19有何影响?
Blood. 2020 Jul 2;136(1):137-139. doi: 10.1182/blood.2020006216.
3
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Front Pediatr. 2023 May 19;11:1200877. doi: 10.3389/fped.2023.1200877. eCollection 2023.
中国武汉成人 COVID-19 住院患者的临床病程和死亡危险因素:一项回顾性队列研究。
Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.
4
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.中国武汉 99 例 2019 年新型冠状病毒肺炎患者的流行病学和临床特征:描述性研究。
Lancet. 2020 Feb 15;395(10223):507-513. doi: 10.1016/S0140-6736(20)30211-7. Epub 2020 Jan 30.
5
Primary infectious costochondritis due to Prevotella nigrescens in an immunocompetent patient: clinical and imaging findings.免疫功能正常患者中普雷沃菌属黑色亚种引起的原发性感染性肋软骨炎:临床和影像学表现。
Skeletal Radiol. 2019 Aug;48(8):1305-1309. doi: 10.1007/s00256-019-3148-0. Epub 2019 Jan 26.
6
Risk factors of serious infections in patients with rheumatoid arthritis treated with tocilizumab in the French Registry REGATE.托珠单抗治疗类风湿关节炎患者严重感染的风险因素:法国 REGATE 注册研究。
Rheumatology (Oxford). 2017 Oct 1;56(10):1746-1754. doi: 10.1093/rheumatology/kex238.
7
C reactive protein may not be reliable as a marker of severe bacterial infection in patients receiving tocilizumab.在接受托珠单抗治疗的患者中,C反应蛋白作为严重细菌感染的标志物可能不可靠。
BMJ Case Rep. 2013 Oct 31;2013:bcr2013010423. doi: 10.1136/bcr-2013-010423.
8
Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab.3例使用托珠单抗治疗的患者发生严重播散性金黄色葡萄球菌感染。
BMJ Case Rep. 2013 Jan 2;2013:bcr2012007413. doi: 10.1136/bcr-2012-007413.
9
Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials.托珠单抗治疗类风湿关节炎患者不良事件(包括严重感染)风险的系统文献回顾和荟萃分析:随机对照试验。
Rheumatology (Oxford). 2011 Mar;50(3):552-62. doi: 10.1093/rheumatology/keq343. Epub 2010 Nov 14.