对首剂过敏的患者中第二剂Moderna和辉瑞-BioNTech新冠病毒mRNA疫苗的分级接种
Graded Administration of Second Dose of Moderna and Pfizer-BioNTech COVID-19 mRNA Vaccines in Patients With Hypersensitivity to First Dose.
作者信息
Tuong Linh-An C, Capucilli Peter, Staicu Mary, Ramsey Allison, Walsh Edward E, Shahzad Mustafa S
机构信息
Division of Allergy and Immunology, Rochester Regional Health, Rochester, New York, USA.
Pharmacy Department, Rochester General Hospital, Rochester, New York, USA.
出版信息
Open Forum Infect Dis. 2021 Oct 6;8(12):ofab507. doi: 10.1093/ofid/ofab507. eCollection 2021 Dec.
Abstract
Two mRNA coronavirus disease 2019 (COVID-19) vaccines, Moderna and Pfizer-BioNTech, require 2 doses for maximum efficacy. This case series reports the safety and immunogenicity of a graded administration of the second dose of the Moderna and Pfizer-BioNTech COVID-19 vaccines in patients with immediate hypersensitivity reactions to the first dose.
摘要
两种2019冠状病毒病（COVID-19）信使核糖核酸（mRNA）疫苗，即莫德纳疫苗和辉瑞-生物科技公司疫苗，需要接种两剂才能达到最大效力。本病例系列报告了对第一剂有速发型超敏反应的患者中，莫德纳和辉瑞-生物科技公司COVID-19疫苗第二剂分级接种的安全性和免疫原性。
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