Fluoro and Agrochemicals Department, CSIR-Indian Institute of Chemical Technology, 500007, Hyderabad, India.
Academy of Scientific and Innovative Research, 201002, Ghaziabad, India.
Chem Asian J. 2022 Feb 1;17(3):e202101269. doi: 10.1002/asia.202101269. Epub 2021 Dec 28.
An efficient cascade annulation protocol was established to access substituted 2-hydroxybenzocarbazoles from alkynylcyclohexadienones and substituted 2-aminophenols under gold catalysis. In this transformation a new C-C, two C-N bonds were formed sequentially and moderate to excellent yields of 2-hydroxybenzocarbazole derivatives were obtained selectively via Meyer-Schuster rearrangement in one-pot.
建立了一种高效的级联环化反应协议，用于在金催化下从炔基环己二烯酮和取代的 2-氨基苯酚中获得取代的 2-羟基苯并咔唑。在这种转化中，通过Meyer-Schuster 重排，在一锅法中顺序形成了新的 C-C 和两个 C-N 键，并以中等至优异的收率选择性地得到了 2-羟基苯并咔唑衍生物。
